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用于帕金森病的丘脑底核深部脑刺激：一种接近循证医学标准的疗法。

Deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a therapy approaching evidence-based standards.

作者信息

Deuschl G, Wenzelburger R, Kopper F, Volkmann J

机构信息

Department of Neurology, Christian-Albrechts-Universität Kiel, Niemannsweg 147, 24105 Kiel, Germany.

出版信息

J Neurol. 2003 Feb;250 Suppl 1:I43-6. doi: 10.1007/s00415-003-1109-8.

DOI:10.1007/s00415-003-1109-8
PMID:12761636
Abstract

DBS of the STN is one of the most promising new therapies for the treatment of PD. However - like many other therapies for PD - the present stage of the scientific assessment does not yet suffice the rigid criteria of evidence-based medicine. Further studies should specifically address the questions of efficacy and side effects as well as the impact on quality of life.

摘要

丘脑底核的深部脑刺激是治疗帕金森病最有前景的新疗法之一。然而，与许多其他帕金森病治疗方法一样，目前的科学评估阶段尚未满足循证医学的严格标准。进一步的研究应具体解决疗效、副作用以及对生活质量影响等问题。

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Deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a therapy approaching evidence-based standards.用于帕金森病的丘脑底核深部脑刺激：一种接近循证医学标准的疗法。
J Neurol. 2003 Feb;250 Suppl 1:I43-6. doi: 10.1007/s00415-003-1109-8.
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Surgery of Parkinson's disease: inclusion criteria and follow-up.帕金森病手术：纳入标准与随访
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Deep brain stimulation: a new treatment for Parkinson's disease.
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Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements.与手指运动相比，丘脑底核刺激治疗帕金森病能更有效地改善近端手臂运动的运动不能症状。
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Bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) or the globus pallidus interna (GPi) for treatment of advanced Parkinson's disease.双侧丘脑底核（STN）或内侧苍白球（GPi）深部脑刺激（DBS）治疗晚期帕金森病。
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Chronic stimulation of the subthalamic nucleus increases daily on-time without dyskinesia in advanced Parkinson's disease.慢性刺激丘脑底核可增加晚期帕金森病患者的每日按时活动时间且不出现运动障碍。
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End of day dyskinesia in advanced Parkinson's disease can be eliminated by bilateral subthalamic nucleus or globus pallidus deep brain stimulation.晚期帕金森病的日间异动症可通过双侧丘脑底核或苍白球内侧部脑深部电刺激得以消除。
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Pallidal vs subthalamic nucleus deep brain stimulation in Parkinson disease.帕金森病中苍白球与丘脑底核深部脑刺激的比较
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Long-term results of bilateral pallidal stimulation in Parkinson's disease.帕金森病双侧苍白球刺激的长期结果
Ann Neurol. 2004 Jun;55(6):871-5. doi: 10.1002/ana.20091.

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