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清洁产品与职业性哮喘

Cleaning products and work-related asthma.

作者信息

Rosenman Kenneth D, Reilly Mary Jo, Schill Donald P, Valiante David, Flattery Jennifer, Harrison Robert, Reinisch Florence, Pechter Elise, Davis Letitia, Tumpowsky Catharine M, Filios Margaret

机构信息

Michigan State University, 117 West Fee Hall, East Lansing, MI 48824, USA.

出版信息

J Occup Environ Med. 2003 May;45(5):556-63. doi: 10.1097/01.jom.0000058347.05741.f9.

Abstract

To describe the characteristics of individuals with work-related asthma associated with exposure to cleaning products, data from the California-, Massachusetts-, Michigan-, and New Jersey state-based surveillance systems of work-related asthma were used to identify cases of asthma associated with exposure to cleaning products at work. From 1993 to 1997, 236 (12%) of the 1915 confirmed cases of work-related asthma identified by the four states were associated with exposure to cleaning products. Eighty percent of the reports were of new-onset asthma and 20% were work-aggravated asthma. Among the new-onset cases, 22% were consistent with reactive airways dysfunction syndrome. Individuals identified were generally women (75%), white non-Hispanic (68%), and 45 years or older (64%). Their most likely exposure had been in medical settings (39%), schools (13%), or hotels (6%), and they were most likely to work as janitor/cleaners (22%), nurse/nurses' aides (20%), or clerical staff (13%). However, cases were reported with exposure to cleaning products across a wide range of job titles. Cleaning products contain a diverse group of chemicals that are used in a wide range of industries and occupations as well as in the home. Their potential to cause or aggravate asthma has recently been recognized. Further work to characterize the specific agents and the circumstances of their use associated with asthma is needed. Additional research to investigate the frequency of adverse respiratory effects among regular users, such as housekeeping staff, is also needed. In the interim, we recommend attention to adequate ventilation, improved warning labels and Material Safety Data Sheets, and workplace training and education.

摘要

为描述与接触清洁用品相关的职业性哮喘患者的特征,我们利用加利福尼亚州、马萨诸塞州、密歇根州和新泽西州基于工作相关哮喘的监测系统数据,来确定与工作中接触清洁用品相关的哮喘病例。1993年至1997年期间,这四个州确认的1915例职业性哮喘病例中,有236例(12%)与接触清洁用品有关。80%的报告为新发哮喘,20%为工作加重性哮喘。在新发病例中,22%符合反应性气道功能障碍综合征。确诊的个体通常为女性(75%)、非西班牙裔白人(68%),年龄在45岁及以上(64%)。他们最有可能接触清洁用品的场所是医疗环境(39%)、学校(13%)或酒店(6%),他们最有可能从事的工作是门卫/清洁工(22%)、护士/护工(20%)或文职人员(13%)。然而,不同职位接触清洁用品的病例均有报告。清洁用品含有多种化学物质,广泛应用于各类行业、职业以及家庭中。其引发或加重哮喘的可能性最近已得到认可。需要进一步开展工作,以明确与哮喘相关的具体制剂及其使用情况。还需要开展额外研究,调查家政人员等经常使用者出现不良呼吸道影响的频率。在此期间,我们建议注意充分通风、改进警示标签和材料安全数据表,并开展工作场所培训和教育。

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