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[再生大鼠肝脏磷脂中脂肪酸的位置分布]

[Positional distribution of fatty acids in the phospholipids of regenerating rat liver].

作者信息

Diatlovitskaia E V, Eĭnisman L I, Mamontov S P, Bergel'son L D

出版信息

Biokhimiia. 1976 Mar;41(3):538-42.

PMID:1276286
Abstract

The fatty acid composition and positioning in the glycerophospholipids from regenerating rat liver were investigated at different stages of the regeneration process. In the lecithins and phosphatidylethanolamines of the regenerating liver the content of arachidonic acid is lower and that of linoleic acid is higher than in the corresponding lipid fractions of normal rat liver. These deviations are maximal at 24 hours after hepatectomy i.e. at the onset of the mitosis. At any stage of the regeneration the high specifity of the fatty acid positioning characteristical for the normal liver is retained completely. The fatty acid composition of cardiolipin is not changed during the regeneration process.

摘要

在肝脏再生过程的不同阶段,对再生大鼠肝脏甘油磷脂中的脂肪酸组成和定位进行了研究。再生肝脏的卵磷脂和磷脂酰乙醇胺中,花生四烯酸的含量低于正常大鼠肝脏相应脂质组分,而亚油酸的含量则高于正常大鼠肝脏相应脂质组分。这些偏差在肝切除术后24小时最大,即有丝分裂开始时。在再生的任何阶段,正常肝脏特有的脂肪酸定位的高特异性都完全保留。在再生过程中,心磷脂的脂肪酸组成没有变化。

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