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[肝脏再生过程中的质膜脂质组成:脂肪酸去饱和程度]

[Plasma membrane lipid composition in liver regeneration: degree of fatty acid desaturation].

作者信息

Bruscalupi G, Mangiantini M T, Spagnuolo S, Trentalance A

出版信息

Boll Soc Ital Biol Sper. 1979 Mar 15;55(5):455-9.

PMID:553601
Abstract

In the context of the biochemical characterization of the plasma membrane during liver regeneration, the fatty acid composition of phospholipids has been determined. Experiments were carried out on liver plasma membrane phospholipid extracts obtained from livers of laparatomized or partially hepatectomized rats 1.5, 4, 15 and 24 h after surgery. The results show no significant change in fatty acid composition and insaturation degree at any time after partial hepatectomy. The results are discussed in view of the lower cholesterol/phospholipid ratio observed in regenerating liver plasma membrane.

摘要

在肝脏再生过程中质膜的生化特性研究背景下,已测定了磷脂的脂肪酸组成。实验是在手术后1.5、4、15和24小时从剖腹或部分肝切除大鼠的肝脏中获取的肝质膜磷脂提取物上进行的。结果显示,部分肝切除后任何时间脂肪酸组成和不饱和度均无显著变化。鉴于在再生肝质膜中观察到较低的胆固醇/磷脂比率,对这些结果进行了讨论。

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