Blendea Mihaela C, McFarlane Samy I, Isenovic Esma R, Gick Gregory, Sowers James R
Department of Medicine, State University of New York Health Science Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Curr Diab Rep. 2003 Jun;3(3):223-9. doi: 10.1007/s11892-003-0068-z.
Both type 1 and type 2 diabetic patients have an increased incidence of ischemic heart disease and congestive heart failure. Cardiovascular disease accounts for up to 80% of the excess mortality in patients with type 2 diabetes. The burden of cardiovascular disease is especially pronounced in diabetic women. Factors that underlie diabetic heart disease include multiple vessel coronary artery disease, long-standing hypertension, metabolic derangements such as hyperglycemia and dyslipidemia, microvascular disease, and autonomic neuropathy. There is also increased sudden death associated with diabetes, which is due, in part, to the underlying autonomic neuropathy. This article reviews diabetic cardiac disease, with an emphasis on type 2 diabetes.
1型和2型糖尿病患者患缺血性心脏病和充血性心力衰竭的几率均有所增加。心血管疾病在2型糖尿病患者的额外死亡率中占比高达80%。心血管疾病的负担在糖尿病女性中尤为明显。糖尿病性心脏病的潜在因素包括多支血管冠状动脉疾病、长期高血压、高血糖和血脂异常等代谢紊乱、微血管疾病以及自主神经病变。糖尿病还会增加猝死风险,部分原因是潜在的自主神经病变。本文综述糖尿病性心脏病,重点关注2型糖尿病。