Okamura Hideyuki, Denawa Masatsugu, Ohniwa Ryosuke, Takeyasu Kunio
Graduate School of Biostudies, Kyoto University, Kitashirakawa-oiwake-cho, Sakyo-ku, Japan.
Ann N Y Acad Sci. 2003 Apr;986:219-23. doi: 10.1111/j.1749-6632.2003.tb07163.x.
The P-type ATPase has become a protein superfamily. On the basis of sequence similarities, the phylogenetic analyses, and substrate specificities, this superfamily can be classified into 5 families and 11 subfamilies. A comparative phylogenetic analysis demonstrates the relationship between the molecular evolution of these subfamilies and the establishment of the kingdoms of living things.