Ichikawa Yasutaka, Sakuma Hajime, Kitagawa Kakuya, Ishida Nanaka, Takeda Kan, Uemura Shoko, Motoyasu Munenobu, Nakano Takeshi, Nozaki Atsushi
Department of Radiology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie 514-8507, Japan.
J Cardiovasc Magn Reson. 2003;5(2):333-42. doi: 10.1081/jcmr-120019422.
Previous studies demonstrated that magnetic resonance (MR) imaging consistently underestimated angiographic measurements of left ventricular (LV) volumes. The purpose of this study was to determine whether MR imaging with steady-state free precession acquisition (SSFP) can provide improved accuracy and reproducibility in measuring cardiac function in comparison with fast spoiled gradient echo cine MR imaging (SPGR). Twenty patients with cardiovascular diseases who underwent breath-hold cine MR imaging within one week of LV angiography were studied. Two sets of breath-hold cine MR images were obtained, one with SSFP and another with SPGR. The LV volumes determined by two breath-hold cine MR sequences were compared with the results by LV angiography. SPGR cine MR imaging consistently underestimated angiographic LV volumes. The mean difference of LV end-diastolic volume was -22.5 +/- 14.8 ml (p < 0.001) for short-axis planes and -27.7 +/- 21.5 ml (p < 0.001) for long-axis planes. In contrast, LV volumes measured by the SSFP imaging showed a good agreement with the results by angiography. The mean difference of LV end-diastolic volume was -2.5 +/- 14.3 ml (p = N.S.) for short-axis planes and -10.9 +/- 15.1 ml (p < 0.01) for long-axis planes. Standard error of the estimation in measuring LV end-diastolic volume with the SSFP imaging was 3.9% for short-axis images and 4.9% for long-axis images. These values were 7.2% and 8.7% with the SPGR imaging. In conclusion, the SSFP acquisition can provide accurate and noninvasive assessments of LV volumes and ejection fraction within a reduced imaging time.
先前的研究表明，磁共振（MR）成像一直低估了左心室（LV）容积的血管造影测量值。本研究的目的是确定与快速扰相梯度回波电影MR成像（SPGR）相比，采用稳态自由进动采集（SSFP）的MR成像在测量心脏功能时是否能提供更高的准确性和可重复性。对20例在左心室血管造影一周内接受屏气电影MR成像的心血管疾病患者进行了研究。获得了两组屏气电影MR图像，一组采用SSFP，另一组采用SPGR。将两种屏气电影MR序列测定的左心室容积与左心室血管造影的结果进行比较。SPGR电影MR成像一直低估了血管造影的左心室容积。短轴平面上左心室舒张末期容积的平均差异为-22.5±14.8 ml（p<0.001），长轴平面上为-27.7±21.5 ml（p<0.001）。相比之下，SSFP成像测量的左心室容积与血管造影结果显示出良好的一致性。短轴平面上左心室舒张末期容积的平均差异为-2.5±14.3 ml（p=无显著性差异），长轴平面上为-10.9±15.1 ml（p<0.01）。用SSFP成像测量左心室舒张末期容积的估计标准误差，短轴图像为3.9%，长轴图像为4.9%。SPGR成像时这些值分别为7.2%和8.7%。总之，SSFP采集可以在缩短的成像时间内对左心室容积和射血分数提供准确的无创评估。
