不同暴露情况儿童的血小板减少症与恶性疟原虫疟疾
Thrombocytopenia and Plasmodium falciparum malaria in children with different exposures.
作者信息
Moulin F, Lesage F, Legros A-H, Maroga C, Moussavou A, Guyon P, Marc E, Gendrel D
机构信息
Hopital Saint Vincent de Paul, Paris, France.
出版信息
Arch Dis Child. 2003 Jun;88(6):540-1. doi: 10.1136/adc.88.6.540.
We studied thrombocytopenia during acute Plasmodium falciparum malaria in 64 traveller children from Paris (France), 85 children from Dakar (Senegal) with an intermittent exposure (69 with severe attack or cerebral malaria), and 81 children from Libreville (Gabon) with a perennial exposure (43 with severe attack or cerebral malaria). Initial thrombocytopenia was present in 43-58% of children with P falciparum malaria but was not more frequent in severe outcome or cerebral malaria. Low parasitaemia may lead to the misdiagnosis of malaria and delayed treatment when there is associated thrombocytopenia
我们研究了来自法国巴黎的64名旅行儿童、来自塞内加尔达喀尔的85名间歇性接触疟原虫（其中69名有严重发作或患脑型疟疾）的儿童以及来自加蓬利伯维尔的81名常年接触疟原虫（其中43名有严重发作或患脑型疟疾）的儿童在急性恶性疟原虫疟疾期间的血小板减少情况。43%-58%的恶性疟原虫疟疾患儿存在初始血小板减少，但在严重结局或脑型疟疾中并不更常见。当合并血小板减少时，低疟原虫血症可能导致疟疾误诊和治疗延迟。
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