Tannirandorn Y, Sangsawang S, Manotaya S, Uerpairojkit B, Samritpradit P, Charoenvidhya D
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Int J Gynaecol Obstet. 2003 Jun;81(3):263-6. doi: 10.1016/s0020-7292(03)00076-6.
To study the incidence of fetal loss in threatened abortion after detection of embryonic/fetal heart activity.
A prospective study was performed on pregnant women with clinically diagnosed threatened abortion between 6 and 14 weeks of gestation. All had a good menstrual history and the calculated gestational age using crown-rump length in the first trimester ultrasound was in agreement. Embryonic/fetal heart rate measurements were obtained by a 5 MHz vaginal probe using M-mode and real-time B mode imaging. All cases were followed up with respect to pregnancy outcomes. The data were analyzed using the SPSS computer program.
Eighty-seven pregnant women were included in the study. There were three pregnancies (3.4%) which resulted in fetal loss before 20 weeks of gestation. In viable pregnancies, the mean embryonic/fetal heart rate increased with advancing gestational age. The individual values of embryonic/fetal heart rate for fetal losses were within the reference range.
The incidence of fetal loss in threatened abortion after detection of embryonic/fetal heart activity was 3.4%. There was no evident pattern of bradycardia or tachycardia that signaled the incipient of viability.
研究检测到胚胎/胎儿心脏活动后先兆流产中胎儿丢失的发生率。
对妊娠6至14周临床诊断为先兆流产的孕妇进行前瞻性研究。所有孕妇月经史良好，且孕早期超声测量头臀长度计算出的孕周一致。使用5MHz阴道探头通过M型和实时B型成像获取胚胎/胎儿心率测量值。对所有病例的妊娠结局进行随访。数据使用SPSS计算机程序进行分析。
87名孕妇纳入研究。有3例妊娠（3.4%）在妊娠20周前导致胎儿丢失。在存活妊娠中，平均胚胎/胎儿心率随孕周增加而升高。胎儿丢失的胚胎/胎儿心率个体值在参考范围内。
检测到胚胎/胎儿心脏活动后先兆流产中胎儿丢失的发生率为3.4%。没有明显的心动过缓或心动过速模式预示存活的开始。
