Tongsong T, Srisomboon J, Wanapirak C, Sirichotiyakul S, Pongsatha S, Polsrisuthikul T
Division of Maternal-Fetal Medicine, Chiangmai University, Thailand.
J Obstet Gynaecol (Tokyo 1995). 1995 Aug;21(4):331-5. doi: 10.1111/j.1447-0756.1995.tb01019.x.
Pregnancy with visible fetal heart beat complicated by first trimester threatened abortion had significant increased risk of subsequent spontaneous abortion compared with normal pregnancy.
To compare pregnancy outcomes in cases complicated by first trimester threatened abortion with those that were not.
Prospective cohort study of 255 cases of first trimester threatened abortions but with visible heart beat and 265 other normal pregnancies.
Spontaneous abortion rates of 5.5% (with relative abortal risk of 2.91) was found for study group, compared to 1.88% for controls (p < 0.05). Preterm delivery was also higher, but was not statistically significant.
First trimester bleeding with visible fetal heart beat appears to associate significantly with higher subsequent spontaneous abortion rate than those without.
与正常妊娠相比，有可见胎心搏动的妊娠合并孕早期先兆流产，其后续自然流产风险显著增加。
比较孕早期先兆流产合并病例与未合并病例的妊娠结局。
对255例孕早期有先兆流产但有可见胎心搏动的病例及265例其他正常妊娠进行前瞻性队列研究。
研究组自然流产率为5.5%（相对流产风险为2.91），而对照组为1.88%（p<0.05）。早产率也较高，但无统计学意义。
孕早期有可见胎心搏动的出血似乎比无此情况者后续自然流产率显著更高。
