Wouters D B, van Horn J R, Bos R R M
Department of General Surgery, Arthroscopic Surgery and Traumatology, Twee Steden Hospital Dr. Deelenlaan 5, 5042 AD, Tilburg, The Netherlands.
Acta Orthop Belg. 2003 Apr;69(2):175-81.
The use of biodegradable fixation devices in the operative treatment of osteochondritis dissecans of the knee could avoid a second operation for removal of the hardware, but what are the disadvantages? Seven osteochondritis dissecans lesions, non-displaced in four adult knees and in one adolescent knee and displaced in two knees of adolescents, were treated by drilling and stabilisation with biodegradable pins, resulting in primary consolidation in the five non-displaced lesions and failure in the two detached lesions. However, two detached fragments in adults, primarily fixed with one metallic compression screw and three biodegradable pins both consolidated. In another adult patient, the fixation with two compression screws failed. A study of the available literature and the results of our limited experience seem to indicate that the primary operative treatment of choice of a non-detached osteochondritis dissecans lesion is drilling and fixation with biodegradable pins. However, if this regimen fails or in patients with a detached lesion, one metallic screw and a few additional biodegradable pins appear to constitute the best method of fixation. The use of biodegradable screws is still hazardous, because of the long degradation time and subsequent risk of erosion of the opposite cartilage and tissue reaction. Other resurfacing options are available for failures or fragmented or non-vital lesions.
在膝关节剥脱性骨软骨炎的手术治疗中使用可生物降解固定装置可避免二次手术取出内固定物,但有哪些缺点呢?对7例剥脱性骨软骨炎病变进行了治疗,其中4例成年膝关节和1例青少年膝关节的病变未移位,2例青少年膝关节的病变移位,通过钻孔并用可生物降解销钉进行固定,5例未移位病变实现了一期愈合,2例分离病变治疗失败。然而,2例成年患者的分离碎片,最初用1枚金属加压螺钉和3枚可生物降解销钉固定均实现了愈合。在另1例成年患者中,用2枚加压螺钉固定失败。对现有文献的研究以及我们有限经验的结果似乎表明,对于未分离的剥脱性骨软骨炎病变,首选的一期手术治疗方法是钻孔并用可生物降解销钉固定。然而,如果该方案失败或对于分离病变的患者,1枚金属螺钉和一些额外的可生物降解销钉似乎构成了最佳的固定方法。由于降解时间长以及随后对相对软骨侵蚀和组织反应的风险,使用可生物降解螺钉仍然存在风险。对于治疗失败、碎片状或无活力的病变,还有其他表面修复选择。