Tutrone William D, Saini Ritu, Caglar Selin, Weinberg Jeffrey M, Crespo Jorge
University of Vermont, Burlington, USA.
Cutis. 2003 May;71(5):365-70.
Actinic keratoses (AKs) are evolving, malignant cutaneous neoplasms. AKs can be treated with physical or destructive methods and with topical therapies. This article is the first in a 2-part series that will review current topical therapeutic options for AKs. Several topical treatment options offer some significant benefit for the alleviation of these lesions. Therapies include 5-fluorouracil, imiquimod, diclofenac, colchicine, and retinoids. The first part of this review will focus on topical 5-fluorouracil and imiquimod.
光化性角化病（AKs）是不断发展的恶性皮肤肿瘤。AKs可用物理或破坏性方法以及局部疗法进行治疗。本文是一个两部分系列文章中的第一篇，该系列将综述目前针对AKs的局部治疗选择。几种局部治疗选择对缓解这些病变有显著益处。治疗方法包括5-氟尿嘧啶、咪喹莫特、双氯芬酸、秋水仙碱和维甲酸。本综述的第一部分将聚焦于局部使用的5-氟尿嘧啶和咪喹莫特。
