Waris Eero, Ashammakhi Nureddin, Happonen Harri, Raatikainen Timo, Kaarela Outi, Törmälä Pertti, Santavirta Seppo, Konttinen Yrjö T
Institute of Biomedicine/Anatomy, Biomedicum Helsinki, University of Helsinki, Finland.
Clin Orthop Relat Res. 2003 May(410):310-9. doi: 10.1097/01.blo.0000063789.32430.c6.
Bioabsorbable implants offer an attractive alternative to metallic implants to stabilize small bone fractures in the hand. Self-reinforced bioabsorbable miniplating for metacarpal fractures was studied in bones from cadavers and compared with standard metallic fixation methods. One hundred twelve fresh-frozen metacarpals from humans had three-point bending and torsional loading after transverse osteotomy followed by fixation using seven methods: (1) dorsal and (2) dorsolateral 2-mm self-reinforced polylactide-polyglycolide 80/20 plating, (3) dorsal and (4) dorsolateral 2-mm self-reinforced poly-L/DL-lactide 70/30 plating, (5) dorsal 1.7-mm titanium plating, (6) dorsal 2.3-mm titanium plating, and (7) crossed 1.25-mm Kirschner wires. In apex dorsal and palmar bending, dorsal self-reinforced polylactide-polyglycolide and poly-L/DL-lactide plates provided stability comparable with dorsal titanium 1.7-mm plating. When the bioabsorbable plates were applied dorsolaterally, apex palmar rigidity was increased and apex dorsal rigidity was decreased. Bioabsorbable platings resulted in higher torsional rigidity than 1.7-mm titanium plating and in failure torque comparable with 2.3-mm titanium plating. Low-profile selfreinforced polylactide-polyglycolide and poly-L/DL-lactide miniplates provide satisfactory biomechanical stability for metacarpal fixation. These findings suggest that bioabsorbable miniplating can be used safely in the clinical stabilization of metacarpal and phalangeal fractures.
生物可吸收植入物为金属植入物提供了一种有吸引力的替代方案,用于稳定手部的小骨折。对尸体骨骼中用于掌骨骨折的自增强生物可吸收微型钢板进行了研究,并与标准金属固定方法进行了比较。112根来自人类的新鲜冷冻掌骨在横向截骨后进行了三点弯曲和扭转加载,然后使用七种方法进行固定:(1)背侧和(2)背外侧2毫米自增强聚丙交酯-聚乙交酯80/20钢板,(3)背侧和(4)背外侧2毫米自增强聚-L/DL-丙交酯70/30钢板,(5)背侧1.7毫米钛板,(6)背侧2.3毫米钛板,以及(7)交叉1.25毫米克氏针。在背侧和掌侧顶点弯曲时,背侧自增强聚丙交酯-聚乙交酯和聚-L/DL-丙交酯钢板提供的稳定性与背侧1.7毫米钛板相当。当生物可吸收钢板应用于背外侧时,掌侧顶点刚度增加,背侧顶点刚度降低。生物可吸收钢板产生的扭转刚度高于1.7毫米钛板,破坏扭矩与2.3毫米钛板相当。低轮廓自增强聚丙交酯-聚乙交酯和聚-L/DL-丙交酯微型钢板为掌骨固定提供了令人满意的生物力学稳定性。这些发现表明,生物可吸收微型钢板可安全用于掌骨和指骨骨折的临床固定。