Prevel C D, Eppley B L, Ge J, Winkler M M, Katona T R, D'Alessio K, Sarver D
Division of Plastic Surgery, University of Kentucky Medical Center, Lexington 40536-0284, USA.
Ann Plast Surg. 1996 Oct;37(4):377-85. doi: 10.1097/00000637-199610000-00006.
Linear (two-dimensional) and three-dimensional (3D) plating systems (Poly-Medics) composed of the resorbable copolymer of polyglycolic acid (PGA) and poly-l-lactic acid (PLLA) (Lactosorb) were studied in vitro. The plates were applied to osteotomized fresh frozen human cadaveric metacarpal bones that were then tested for torsional rigidity and three-point bending strength and rigidity. The results were compared to those from another study of two low-profile titanium plating systems (Leibinger and Synthes). Analysis of variance revealed that the linear-flat Lactosorb plate and screws had apex dorsal rigidity and force-to-displacement measurements equal to all but two of the titanium plates (3D). The 3D-flat Lactosorb plate had the highest torsional rigidity of the resorbable system, but it was only moderately rigid compared to the titanium plating systems. This in vitro biomechanical study of the copolymer PGA-PLLA plating system indicates that, in clinical applications, it may be better suited for metacarpal fractures rather than proximal phalangeal fractures due to the lower demands of torsional loading compared to apex bending.
对由聚乙醇酸（PGA）和聚左旋乳酸（PLLA）的可吸收共聚物（Lactosorb）组成的线性（二维）和三维（3D）接骨板系统（Poly-Medics）进行了体外研究。将这些接骨板应用于新鲜冷冻的人尸体掌骨截骨处，然后对其进行扭转刚度以及三点弯曲强度和刚度测试。将结果与另一项关于两种低轮廓钛接骨板系统（Leibinger和Synthes）的研究结果进行比较。方差分析显示，线性扁平Lactosorb接骨板和螺钉的顶点背侧刚度以及力-位移测量值与除两块钛接骨板（3D）外的所有钛接骨板相当。3D扁平Lactosorb接骨板在可吸收系统中具有最高的扭转刚度，但与钛接骨板系统相比，其刚度仅为中等。这项关于共聚物PGA-PLLA接骨板系统的体外生物力学研究表明，在临床应用中，由于与顶点弯曲相比扭转负荷要求较低，它可能更适合掌骨骨折而非近端指骨骨折。
