[慢性乙型肝炎患者与健康相关的长期生活质量]
[Long-term health-related quality of life in chronic hepatitis B patients].
作者信息
Wu Gui-cheng, Zhou Wei-ping, Zhao You-rong, Guo Shu-hua, Wang Zhi-yi, Zou Shu-bi, Zhang Quan-hai, Ren Hong, Huang Ai-long, Zhang Ding-feng
机构信息
Institute for Viral Hepatitis, Chongqing University of Medical Sciences, Chongqing 400010, China.
出版信息
Zhonghua Gan Zang Bing Za Zhi. 2003 May;11(5):275-7.
OBJECTIVE
To evaluate their long-term outcome and the efficacy and economic significance of antiviral drugs by investigating the long-term health-related quality of life (HQL) in chronic hepatitis B (CHB) patients.
METHODS
The HQL of 101 CHB patients with biopsy-proven 6 to 18 years ago and 105 persons of general population as control was studied with revised SF-36 questionnaire.
RESULTS
The HQL in CHB patients was lower than that in general population in physical functioning, role physical, general health, mental health, and specific symptoms (mu > or = 2.10, P<0.05).
CONCLUSIONS
The long-term HQL in chronic hepatitis B patients is poor.
目的
通过调查慢性乙型肝炎（CHB）患者与健康相关的长期生活质量（HQL），评估其长期预后以及抗病毒药物的疗效和经济意义。
方法
采用修订的SF - 36问卷对101例经活检证实于6至18年前患病的CHB患者以及105名作为对照的普通人群的HQL进行研究。
结果
CHB患者在生理功能、身体角色、总体健康、心理健康和特定症状方面的HQL低于普通人群（μ≥2.10，P < 0.05）。
结论
慢性乙型肝炎患者的长期HQL较差。
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