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基于对肝炎后肝硬化的评估的中医肝病证候量表和慢性肝病问卷的比较研究。

Comparative Study of TCM Syndrome Scale for Liver Disease and Chronic Liver Disease Questionnaire Based on Assessment of Posthepatitic Cirrhosis.

机构信息

Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shuguang Hospital-Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai 201203, China.

出版信息

Evid Based Complement Alternat Med. 2012;2012:496575. doi: 10.1155/2012/496575. Epub 2012 May 29.

Abstract

Objective. To compare and analyze the relevance and applied value of chronic liver disease questionnaire (CLDQ) and Traditional Chinese Medicine liver disease questionnaire (TCMLDQ) in patients with posthepatitic cirrhosis. Methods. The data of 146 patients' scales of CLDQ and TCMLDQ which based on the characteristics of chinese medical symptoms were collected. We made comparative analysis of the relationship between these two scales by the linear regression model and canonical correlation method and evaluated the advantages and disadvantages of two scales about its items setting and dimension definition. Result. There is a negative correlation in total scores between the two scales and the linear regression equation: CLDQ = 239.38 - 1.232TCMLDQ. The further canonical correlation analysis was used to analyze the two extracted canonical correlative variables with significances (P < 0.05), and the results showed that the overall negative correlation between the two scales mainly came from contributions of both the four dimensions of TCMLDQ (CS, GSYX, GYPX, and OS) and the five dimensions of CLDQ (AS, FA, SS, AC, and EF). Conclusion. These two scales have good consistency in the evaluation of severity and life quality of liver cirrhosis patients, so we suggested that TCMLDQ can be used to evaluate the severity and life quality of patients with posthepatitic cirrhosis.

摘要

目的。比较和分析慢性肝病问卷(CLDQ)和中医肝病问卷(TCMLDQ)在肝炎后肝硬化患者中的相关性和应用价值。方法。收集了 146 例患者 CLDQ 和 TCMLDQ 量表的数据,这些数据基于中医症状特征。我们通过线性回归模型和典型相关方法对这两个量表之间的关系进行了对比分析,并评估了两个量表在其项目设置和维度定义方面的优缺点。结果。两个量表的总分之间存在负相关,线性回归方程为:CLDQ=239.38-1.232TCMLDQ。进一步的典型相关分析用于分析具有显著性意义(P<0.05)的两个提取的典型相关变量,结果表明,两个量表之间的总体负相关主要来自 TCMLDQ 的四个维度(CS、GSYX、GYPX 和 OS)和 CLDQ 的五个维度(AS、FA、SS、AC 和 EF)的共同贡献。结论。这两个量表在评估肝硬化患者的严重程度和生活质量方面具有良好的一致性,因此我们建议 TCMLDQ 可用于评估肝炎后肝硬化患者的严重程度和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4712/3369239/a9e462a150f5/ECAM2012-496575.001.jpg

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