Sicherer Scott H
Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, New York 10029-6574, USA.
Pediatrics. 2003 Jun;111(6 Pt 3):1609-16.
Gastrointestinal food allergies are a spectrum of disorders that result from adverse immune responses to dietary antigens. The named disorders include immediate gastrointestinal hypersensitivity (anaphylaxis), oral allergy syndrome, allergic eosinophilic esophagitis, gastritis, and gastroenterocolitis; dietary protein enterocolitis, proctitis, and enteropathy; and celiac disease. Additional disorders sometimes attributed to food allergy include colic, gastroesophageal reflux, and constipation. The pediatrician faces several challenges in dealing with these disorders because diagnosis requires differentiating allergic disorders from many other causes of similar symptoms, and therapy requires identification of causal foods, application of therapeutic diets and/or medications, and monitoring for resolution of these disorders. This review catalogs the spectrum of gastrointestinal food allergies that affect children and provides a framework for a rational approach to diagnosis and management.
胃肠道食物过敏是一系列由对饮食抗原的不良免疫反应引起的疾病。命名的疾病包括速发型胃肠道超敏反应（过敏反应）、口腔过敏综合征、过敏性嗜酸性食管炎、胃炎和胃肠结肠炎；饮食蛋白性小肠结肠炎、直肠炎和肠病；以及乳糜泻。有时归因于食物过敏的其他疾病包括腹绞痛、胃食管反流和便秘。儿科医生在处理这些疾病时面临几个挑战，因为诊断需要将过敏性疾病与许多其他具有相似症状的病因区分开来，而治疗需要确定致病食物、应用治疗性饮食和/或药物，以及监测这些疾病的缓解情况。本综述对影响儿童的胃肠道食物过敏谱进行了分类，并为合理的诊断和管理方法提供了框架。
