接受单侧睾丸切除术和预防性放射治疗的患者是否存在特征性的精子形态异常？
Do characteristic spermatozoal morphological abnormalities exist in patients who have undergone unilateral orchiectomy and preventive radiotherapy?
作者信息
Panidis Dimitrios, Rousso David, Matalliotakis Ioannis, Kourtis Anargyros, Mavromatidis Georgios, Mamopoulos Michael, Koumantakis Evgenios
机构信息
Third Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Greece.
出版信息
Int J Fertil Womens Med. 2003 Mar-Apr;48(2):83-7.
DESIGN
We examined 16 men who had been subjected to unilateral orchiectomy owing to seminoma and to preventive radiotherapy, in order to investigate the morphologic abnormalities of the spermatozoa (headless and small-round-headedness) that may contribute to infertility.
RESULTS
The same morphologic abnormalities of the head and neck found in the semen samples of fertile men were also found in the semen samples of the patients, albeit in higher percentages; the morphologic abnormalities of the tail in the semen samples of the patients were similar to those of the fertile men, both qualitatively and quantitatively.
CONCLUSION
No specifically characteristic morphologic abnormalities of the spermatozoa were detected in men who were subjected to unilateral orchiectomy and to preventive radiotherapy in comparison with fertile men. The percentage rate of morphologic tail abnormalities is not affected by preventive radiotherapy.
设计
我们检查了16名因精原细胞瘤接受单侧睾丸切除术并接受预防性放疗的男性，以研究可能导致不育的精子形态异常（无头和小圆形头）。
结果
在患者的精液样本中也发现了与可育男性精液样本中相同的头部和颈部形态异常，尽管比例更高；患者精液样本中尾部的形态异常在定性和定量方面与可育男性相似。
结论
与可育男性相比，接受单侧睾丸切除术和预防性放疗的男性未检测到精子特有的形态异常。预防性放疗不影响形态学尾部异常的发生率。
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