Panidis D, Matalliotakis I, Papathanasiou K, Roussos C, Koumantakis E
3rd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece.
Eur J Obstet Gynecol Reprod Biol. 1998 Oct;80(2):247-50. doi: 10.1016/s0301-2115(98)00115-8.
Two new indices, the sperm deformity and the sperm multiple anomalies index, were assessed in 16 male patients who underwent unilateral orchectomy owing to seminoma and in preventive radiotherapy of paraortic and of the iliac lymph glands homolateral to the testis excised. The aim was to assess the value of these two morphological sperm parameters in distinguishing the semen between the above mentioned group of men from the semen of men with other causes of infertility. It was found that: (1) the values of the sperm deformity index and those of the sperm multiple anomalies index were not significantly different between men who underwent unilateral orchectomy and preventive radiotherapy and the men with other causes of subfertility and (2) the values of the above indices were significantly higher in the semen specimens of men who underwent unilateral orchectomy and preventive radiotherapy and in the semen specimens of men with other causes of subfertility than in the semen specimens of fertile men. It is concluded that testicular response, as far as sperm morphology is concerned, is the same irrespective of the cause exerting a negative effect on spermatogenesis.
对16例因精原细胞瘤接受单侧睾丸切除术以及对切除睾丸同侧的腹主动脉旁和髂淋巴结进行预防性放疗的男性患者,评估了两个新指标,即精子畸形率和精子多重异常指数。目的是评估这两个精子形态学参数在区分上述男性组精液与其他不育原因男性精液方面的价值。结果发现:(1)接受单侧睾丸切除术和预防性放疗的男性与其他亚生育原因男性之间,精子畸形指数值和精子多重异常指数值无显著差异;(2)接受单侧睾丸切除术和预防性放疗的男性精液标本以及其他亚生育原因男性精液标本中上述指标的值,显著高于生育男性精液标本中的值。得出的结论是,就精子形态而言,无论对精子发生产生负面影响的原因是什么,睾丸反应都是相同的。