Baredes Soly, Ludwin Danielle B, Troublefield Yolanda L, Langer Paul D, Mirani Neena
Division of Otolaryngology-Head and Neck Surgery, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark 07103-2714, USA.
Laryngoscope. 2003 Jun;113(6):940-2. doi: 10.1097/00005537-200306000-00005.
To present the clinical presentation, workup, surgical approach, and pathological findings of the first case report of a patient with adenocarcinoma ex-pleomorphic adenoma of the lacrimal sac and nasolacrimal duct.
Retrospective review of the records of a case of adenocarcinoma ex-pleomorphic adenoma of the lacrimal sac and nasolacrimal duct.
The clinical presentation, workup, surgical approach, and pathological findings were reviewed.
A 51-year-old man presented with a 10-year history of recurrent epiphora of the right eye. At dacryocystorhinostomy a small lesion was visualized within the lumen of the lacrimal sac. A biopsy specimen was consistent with adenocarcinoma. En bloc resection was accomplished using a lateral rhinotomy and medial maxillectomy. The final specimen showed adenocarcinoma ex-pleomorphic adenoma. The patient was given postoperative radiation therapy. He was free of disease 16 months after treatment.
Lacrimal sac tumors should be considered in the differential diagnosis of chronic epiphora. Management of nasolacrimal adenocarcinoma requires complete surgical resection. Radiation treatment in and of itself is not curative but may be useful as adjuvant therapy. Carcinoma ex-pleomorphic adenoma can develop in the lacrimal sac and nasolacrimal duct.
介绍首例泪囊及鼻泪管多形性腺瘤恶变腺癌患者的临床表现、检查、手术方法及病理结果。
对一例泪囊及鼻泪管多形性腺瘤恶变腺癌患者的病历进行回顾性分析。
回顾临床表现、检查、手术方法及病理结果。
一名51岁男性，有右眼反复溢泪10年病史。在泪囊鼻腔吻合术中，在泪囊腔内可见一个小病变。活检标本符合腺癌。采用外侧鼻切开术和内侧上颌骨切除术进行整块切除。最终标本显示为多形性腺瘤恶变腺癌。患者术后接受了放射治疗。治疗后16个月无疾病复发。
慢性溢泪的鉴别诊断应考虑泪囊肿瘤。鼻泪管腺癌的治疗需要完整的手术切除。放射治疗本身不能治愈，但作为辅助治疗可能有用。多形性腺瘤恶变腺癌可发生于泪囊及鼻泪管。
