Ouhayoun J-P
Department of Periodontology, University Paris 7, Paris, France.
J Clin Periodontol. 2003;30 Suppl 5:10-2. doi: 10.1034/j.1600-051x.30.s5.4.x.
The interaction between saliva-coated tooth surfaces and pathogenic bacteria is partly governed by electrostatic and hydrophobic interactions, providing a solid rationale for using chemical agents as part of a plaque-control routine. Chlorhexidine works in several ways. For example, it binds to salivary mucins on the bacterial cell membrane, and penetrates the plaque biofilm. Essential oil (EO) mouthwashes kill micro-organisms by disrupting their cell walls and inhibiting their enzymic activity. They prevent bacterial aggregation, slow multiplication and extract endotoxins. Recent studies have shown that bacterial phenotypes are altered when organisms change from a planktonic to a sessile state. This suggests that an effective mouthwash must also penetrate the plaque biofilm. Two studies have demonstrated the ability of an EO mouthwash to penetrate the plaque biofilm.
唾液包裹的牙齿表面与致病细菌之间的相互作用部分受静电和疏水相互作用的支配，这为使用化学制剂作为菌斑控制常规方法的一部分提供了坚实的理论依据。洗必泰有多种作用方式。例如，它与细菌细胞膜上的唾液粘蛋白结合，并穿透菌斑生物膜。精油漱口水通过破坏微生物的细胞壁并抑制其酶活性来杀死微生物。它们可防止细菌聚集、减缓繁殖并提取内毒素。最近的研究表明，当微生物从浮游状态转变为固着状态时，其细菌表型会发生改变。这表明一种有效的漱口水还必须穿透菌斑生物膜。两项研究已经证明了一种精油漱口水穿透菌斑生物膜的能力。
