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口腔抗菌剂对牙菌斑的疗效:一项体内研究

Effectiveness of Oral Antiseptics on Tooth Biofilm: A Study in vivo.

作者信息

Mouchrek Junior José Carlos Elias, Nunes Lívia Helena de Araújo Castro, Arruda Cleidiane Silveira, Rizzi Claudia de Castro, Mouchrek Adriana Quinzeiro E Silva, Tavarez Rudys Rodolfo De Jesus, Tonetto Mateus Rodrigues, Bandeca Matheus Coelho, Maia Filho Etevaldo Matos

机构信息

Department of Dentistry, CEUMA University, Sao Luis, MA Brazil.

Department of Postgraduate in Dentistry, CEUMA University, Sao Luis, MA, Brazil.

出版信息

J Contemp Dent Pract. 2015 Aug 1;16(8):674-8. doi: 10.5005/jp-journals-10024-1739.

DOI:10.5005/jp-journals-10024-1739
PMID:26423504
Abstract

AIM

To evaluate the effectiveness of five different mouthwashes through measurement of the plaque index.

MATERIALS AND METHODS

Fifty subjects took part in this blind study, randomized into blocks of five groups according to the active ingredient of the mouthwash: CHX group (0.12% chlorhexidine gluconate), essential oils (EO) group, cetylpyridinium chloride (CPC) group, Tri group (triclosan) and Hamamelis virginiana (HV) group. All subjects were evaluated for a reduction in the bacterial plaque index at 7, 14 and 21 days.

RESULTS

There was a significant reduction in the mean plaque index during the period of evaluation (p < 0.01), and the reduction during the period of evaluation was different between mouthwashes (p < 0.01). The reduction in the plaque index at the end of 21 days was, in decreasing order, CHX > EO > CPC > Tri > HV.

CONCLUSION

The reduction in the plaque index during the period of evaluation was different between the types of mouth-wash. The mouthwash containing the active ingredient chlorhexidine was the most effective, followed by the essential oil, cetylpyridinium chloride, triclosan and H. virginiana.

摘要

目的

通过测量菌斑指数评估五种不同漱口水的效果。

材料与方法

五十名受试者参与了这项盲法研究,根据漱口水的活性成分随机分为五个组:洗必泰组(0.12%葡萄糖酸氯己定)、精油组(EO)、西吡氯铵组(CPC)、三氯生组(Tri)和北美金缕梅组(HV)。在第7天、14天和21天对所有受试者的菌斑指数降低情况进行评估。

结果

在评估期间平均菌斑指数有显著降低(p < 0.01),且不同漱口水在评估期间的降低情况有所不同(p < 0.01)。21天结束时菌斑指数的降低情况从高到低依次为:洗必泰 > 精油 > 西吡氯铵 > 三氯生 > 北美金缕梅。

结论

不同类型漱口水在评估期间菌斑指数的降低情况不同。含活性成分氯己定的漱口水最有效,其次是精油、西吡氯铵、三氯生和北美金缕梅。

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