Dix F P, Brooke R, McCollum C N
Department of Vascular Surgery, South Manchester University Hospitals NHS Trust, Wythenshawe Hospital, Manchester, U.K.
Eur J Vasc Endovasc Surg. 2003 Jun;25(6):556-61. doi: 10.1053/ejvs.2002.1885.
to investigate the relationship between clinical severity of venous disease, calf muscle pump dysfunction and range of ankle movement (ROAM).
ROAM was assessed by goniometry in the supine, nonweightbearing position. Calf muscle pump function was assessed by ambulatory venous pressure (AVP), calculating the pressure relief index (PRI). Venous disease was classified according to the CEAP classification (International Consensus Committee reporting standards on venous disease). Forty seven limbs in 38 adults were recruited and matched for age: 11 normal controls CEAP(0), 12 varicose veins CEAP(2), 12 chronic venous insufficiency CEAP(4,5) and 12 active ulceration CEAP(6).
mean (S.E.M.) age was 60.7 (1.3) years. Mean (S.E.M.) PRI was 1959.6 (313.7) in CEAP(0), 905.3 (139.3) in CEAP(2), 596.5 (148.5) in CEAP(4,5) and 170.6 (69.0) in CEAP(6) (p < 0.001, ANOVA). Mean (S.E.M.) ROAM was 61.3 (2.0) degrees in CEAP(0), but significantly reduced to 49.7 (2.0) in CEAP(2), 42.1 (2.6) in CEAP(4,5) and 40.9 (2.7) in CEAP(6) (p < 0.004, ANOVA post hoc Tukey). PRI correlated with ROAM (p < 0.001, Pearson correlation coefficientr = 0.52).
limbs with venous hypertension have a reduced range of ankle movement related to the clinical severity of venous disease.
研究静脉疾病的临床严重程度、小腿肌肉泵功能障碍与踝关节活动范围（ROAM）之间的关系。
在仰卧、非负重位通过角度测量法评估ROAM。通过动态静脉压（AVP）评估小腿肌肉泵功能，计算压力缓解指数（PRI）。根据CEAP分类（静脉疾病国际共识委员会报告标准）对静脉疾病进行分类。招募了38名成年人的47条肢体，并按年龄匹配：11名正常对照CEAP(0)，12名静脉曲张CEAP(2)，12名慢性静脉功能不全CEAP(4,5)和12名活动性溃疡CEAP(6)。
平均（标准误）年龄为60.7（1.3）岁。CEAP(0)组的平均（标准误）PRI为1959.6（313.7），CEAP(2)组为905.3（139.3），CEAP(4,5)组为596.5（148.5），CEAP(6)组为170.6（69.0）（p<0.001，方差分析）。CEAP(0)组的平均（标准误）ROAM为61.3（2.0）度，但在CEAP(2)组显著降至49.7（2.0）度，CEAP(4,5)组为42.1（2.6）度，CEAP(6)组为40.9（2.7）度（p<0.004，方差分析后Tukey检验）。PRI与ROAM相关（p<0.001，Pearson相关系数r=0.52）。
静脉高压肢体的踝关节活动范围减小，且与静脉疾病的临床严重程度相关。
