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Factors that influence healing of chronic venous leg ulcers: a retrospective cohort.影响下肢慢性静脉溃疡愈合的因素:一项回顾性队列研究。
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Sample size calculation in medical studies.医学研究中的样本量计算。
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Pentoxifylline for treating venous leg ulcers.己酮可可碱治疗下肢静脉性溃疡
Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD001733. doi: 10.1002/14651858.CD001733.pub3.
7
Randomized study assessing the influence of supervised exercises on ankle joint mobility in patients with venous leg ulcerations.随机研究评估监督锻炼对静脉溃疡患者踝关节活动度的影响。
Arch Med Sci. 2010 Dec;6(6):956-63. doi: 10.5114/aoms.2010.19308. Epub 2010 Dec 29.
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Diagnosis and treatment of venous ulcers.静脉性溃疡的诊断与治疗
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Venous ulcers.静脉性溃疡
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[Differential diagnoses in leg ulcers].[腿部溃疡的鉴别诊断]
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多米尼加共和国整脊移动诊所就诊人群中下肢静脉溃疡与踝关节活动范围的关联

Association of Venous Leg Ulcers With Ankle Range of Motion in People Attending Chiropractic Mobile Clinics in the Dominican Republic.

作者信息

Tavares Patricia A, Landsman Victoria, Gomez Nathalie, Ferreiras Ariel, Lopez Ramon A

机构信息

Division of Clinical Education, Canadian Memorial Chiropractic College, North York, Ontario, Canada.

Division of Graduate Education and Research, Canadian Memorial Chiropractic College, North York, Ontario, Canada.

出版信息

J Chiropr Med. 2017 Dec;16(4):263-270. doi: 10.1016/j.jcm.2017.08.004. Epub 2017 Oct 11.

DOI:10.1016/j.jcm.2017.08.004
PMID:29276458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5731840/
Abstract

OBJECTIVE

The goal of the study was to determine if there was an association between chronic venous disorders (CVDs), particularly venous leg ulcers, and ankle range of motion (ROM) in the Dominican Republic.

METHODS

Chronic venous disorders were classified using the clinical manifestations portion (C) of the CEAP (clinical manifestations, etiology, anatomy, pathophysiology) method. The legs of participants attending mobile chiropractic clinics in rural, low-income areas in the Dominican Republic were assessed for clinical signs of CVD and venous ulcers. Ankle ROM was then measured, and photographs of the legs were taken. The 6 clinical stages of CVD were divided into 3 groups: normal legs (normal), no ulcer CVD, and ulcer CVD (healed and active). Multiple linear regression of ankle ROM against CVD grouping was used to test the association.

RESULTS

Eight of the 837 patients for whom CVD classification was obtained had venous ulcers (healed or active) on at least 1 leg. About 30% relative reduction in ROM (ankle dorsiflexion plus plantar flexion) was observed between the ulcer group and the normal group. Regression analysis comparing legs with ulcers to healthy legs (normal), adjusted for age, gender, indicator for obesity, and previous leg trauma, revealed a significant decrease of approximately 14° ( = .0007) in ankle ROM. Age was also found to be strongly significant in the regression analysis, 1 year of aging was associated with a decrease of 0.16° ( < .0001) in ankle ROM (approximately 1.6° in 10 years).

CONCLUSION

A significant decrease was observed in ankle ROM for participants with active and healed leg venous ulcers compared with those without ulcers. There appeared to be an association between venous leg ulcers and ankle ROM in this sample.

摘要

目的

本研究的目的是确定在多米尼加共和国慢性静脉疾病(CVDs),尤其是下肢静脉溃疡与踝关节活动范围(ROM)之间是否存在关联。

方法

使用CEAP(临床表现、病因、解剖、病理生理学)方法的临床表现部分(C)对慢性静脉疾病进行分类。对在多米尼加共和国农村低收入地区流动脊骨神经科诊所就诊的参与者的腿部进行CVD和静脉溃疡临床体征评估。然后测量踝关节ROM,并拍摄腿部照片。CVD的6个临床阶段分为3组:正常腿部(正常)、无溃疡CVD和溃疡CVD(愈合和活动期)。使用踝关节ROM对CVD分组的多元线性回归来检验这种关联。

结果

在获得CVD分类的837名患者中,有8名患者至少有1条腿患有静脉溃疡(愈合或活动期)。在溃疡组和正常组之间观察到ROM(踝关节背屈加跖屈)相对降低约30%。将有溃疡的腿与健康腿(正常)进行回归分析,并对年龄、性别、肥胖指标和既往腿部创伤进行校正,结果显示踝关节ROM显著降低约14°(P = .0007)。在回归分析中还发现年龄具有很强的显著性,年龄每增加1岁,踝关节ROM降低0.16°(P < .0001)(10年约降低1.6°)。

结论

与没有溃疡的参与者相比,患有活动期和愈合期腿部静脉溃疡的参与者踝关节ROM显著降低。在这个样本中,下肢静脉溃疡与踝关节ROM之间似乎存在关联。