Kadoya Satoru, Iizuka Hideaki, Nakamura Tsutomu
Department of Neurosurgery, Kanazawa Medical University, Ishikawa, Japan.
Neurol Med Chir (Tokyo). 2003 May;43(5):228-40; discussion 241. doi: 10.2176/nmc.43.228.
Long-term follow-up results were examined to verify the efficacy of anterior osteophytectomy for cervical spondylotic myelopathy and radiculopathy, in particular the outcome for patients with developmentally narrow cervical canals and patients with associated ossification of the posterior longitudinal ligament (OPLL). One hundred thirty-nine patients who had undergone anterior osteophytectomy with interbody fusion between 1976 and 1990 were followed up for 1 to 22.5 years (mean 11.4 years). Overall results evaluated by the neurosurgical cervical spine scale scoring and grading showed significant improvement in both improvement score (2.7 +/- 2.3) and improvement rate (52.3 +/- 45.7%). Lower extremity motor function improved in 66.1% of patients, upper extremity motor function in 82.0%, and sensory/pain function in 70.5%. Improvement ranged from one to three grades. Severely affected patients showed good recovery. Outcome for patients with narrow cervical canals (41 patients, 29.5%) did not differ significantly from that for patients with normal canals (98, 70.5%). Patients with associated OPLL (32 patients, 23.0%) had approximately the same outcomes as those with only spondylosis (107, 77.0%). Fifteen patients (10.8%) underwent reoperation because of myelopathy due to disc degeneration adjacent to the fused level (11 patients) or OPLL (4 patients). Anterior osteophytectomy with interbody fusion can achieve good outcomes in patients with cervical spondylotic myelopathy and radiculopathy, regardless of the size of the spinal canal and association with OPLL.
研究长期随访结果,以验证前路骨赘切除术治疗脊髓型颈椎病和神经根型颈椎病的疗效,尤其是发育性颈椎管狭窄患者以及合并后纵韧带骨化(OPLL)患者的治疗效果。对1976年至1990年间接受前路骨赘切除并椎间融合术的139例患者进行了1至22.5年(平均11.4年)的随访。根据神经外科颈椎评分量表进行的总体结果评估显示,改善评分(2.7±2.3)和改善率(52.3±45.7%)均有显著改善。66.1%的患者下肢运动功能改善,82.0%的患者上肢运动功能改善,70.5%的患者感觉/疼痛功能改善。改善程度为一至三级。重度患者恢复良好。颈椎管狭窄患者(41例,29.5%)的治疗效果与椎管正常患者(98例,70.5%)相比无显著差异。合并OPLL的患者(32例,23.0%)与仅患有颈椎病的患者(107例,77.0%)的治疗效果大致相同。15例患者(10.8%)因融合节段相邻椎间盘退变(11例)或OPLL(4例)导致脊髓病而接受了再次手术。前路骨赘切除并椎间融合术可使脊髓型颈椎病和神经根型颈椎病患者获得良好的治疗效果,无论椎管大小以及是否合并OPLL。