Mostashari Farzad, Fine Annie, Das Debjani, Adams John, Layton Marcelle
Bureau of Epidemiology Services, New York City Department of Health and Mental Hygiene, New York, NY 10013, USA.
J Urban Health. 2003 Jun;80(2 Suppl 1):i43-9. doi: 10.1007/pl00022314.
In 1998, the New York City Department of Health and the Mayor's Office of Emergency Management began monitoring the volume of ambulance dispatch calls as a surveillance tool for biologic terrorism. We adapted statistical techniques designed to measure excess influenza mortality and applied them to outbreak detection using ambulance dispatch data. Since 1999, we have been performing serial daily regressions to determine the alarm threshold for the current day. In this article, we evaluate this approach by simulating a series of 2,200 daily regressions. In the influenza detection implementation of this model, there were 71 (3.2%) alarms at the 99% level. Of these alarms, 64 (90%) occurred shortly before or during a period of peak influenza in each of six influenza seasons. In the bioterrorism detection implementation of this methodology, after accounting for current influenza activity, there were 24 (1.1%) alarms at the 99% level. Two occurred during a large snowstorm, 1 is unexplained, and 21 occurred shortly before or during a period of peak influenza activity in each of six influenza seasons. Our findings suggest that this surveillance system is sensitive to communitywide respiratory outbreaks with relatively few false alarms. More work needs to be done to evaluate the sensitivity of this approach for detecting nonrespiratory illness and more localized outbreaks.
1998年,纽约市卫生部门和市长办公室应急管理部门开始监测救护车调度呼叫量,将其作为生物恐怖主义的监测工具。我们采用了旨在测量流感超额死亡率的统计技术,并将其应用于利用救护车调度数据进行疫情检测。自1999年以来,我们一直在进行每日序列回归,以确定当日的警报阈值。在本文中,我们通过模拟一系列2200次每日回归来评估这种方法。在该模型的流感检测实施中,在99%的水平上有71次(3.2%)警报。在这些警报中,64次(90%)发生在六个流感季节中每个季节流感高峰期之前或期间不久。在该方法的生物恐怖主义检测实施中,在考虑当前流感活动后,在99%的水平上有24次(1.1%)警报。两次发生在一场大雪期间,一次原因不明,21次发生在六个流感季节中每个季节流感活动高峰期之前或期间不久。我们的研究结果表明,这种监测系统对社区范围内的呼吸道疫情敏感,误报相对较少。需要做更多工作来评估这种方法对检测非呼吸道疾病和更局部疫情的敏感性。