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近距离放射治疗的进展:针对乳腺癌的新方法

Advances in brachytherapy: new approaches to target breast cancer.

作者信息

Hogle William P, Quinn Annette E, Heron Dwight E

出版信息

Clin J Oncol Nurs. 2003 May-Jun;7(3):324-8. doi: 10.1188/03.CJON.324-328.

DOI:10.1188/03.CJON.324-328
PMID:12793340
Abstract

Advances in breast brachytherapy techniques have led to the development of new approaches for treatment of patients with early-stage breast cancer. This article reviews the indications, clinical utility, and nursing interventions for the Mammosite Radiation Therapy System (Proxima Therapeutics, Alpharetta, GA) and INTRABEAM (Photoelectron Corporation, North Billerica, MA) radiation therapy system. Each uses a slightly different approach to provide definitive radiotherapy to the breast tumor bed following excision. Radiation oncology nurses should have an understanding of how each system works to provide optimal care as it pertains to education, side effect management, and catheter care for patients receiving each of these types of radiotherapy. These innovative alternatives will greatly reduce required treatment time if clinical studies find them to be equivocal or superior to traditional radiation therapy techniques. These treatment approaches also may make radiation treatments more convenient for women with early-stage breast cancer.

摘要

乳腺近距离放射治疗技术的进步促使了早期乳腺癌患者治疗新方法的发展。本文回顾了Mammosite放射治疗系统(Proxima Therapeutics公司,佐治亚州阿尔法利塔)和INTRABEAM放射治疗系统(光电子公司,马萨诸塞州北比勒里卡)的适应症、临床应用及护理干预措施。二者在切除术后为乳腺肿瘤床提供根治性放射治疗时采用的方法略有不同。放射肿瘤学护士应了解每个系统的工作原理,以便在对接受此类放射治疗的患者进行教育、副作用管理及导管护理时提供最佳护理。如果临床研究发现这些创新方法与传统放射治疗技术等效或更优,那么它们将大大缩短所需的治疗时间。这些治疗方法也可能会让早期乳腺癌女性的放射治疗更加便利。

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Advances in brachytherapy: new approaches to target breast cancer.近距离放射治疗的进展:针对乳腺癌的新方法
Clin J Oncol Nurs. 2003 May-Jun;7(3):324-8. doi: 10.1188/03.CJON.324-328.
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Five-year results: the initial clinical trial of MammoSite balloon brachytherapy for partial breast irradiation in early-stage breast cancer.五年结果:MammoSite球囊近距离放射疗法用于早期乳腺癌局部乳腺照射的初步临床试验
Am J Surg. 2007 Oct;194(4):456-62. doi: 10.1016/j.amjsurg.2007.06.010.
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Clinical experience with the MammoSite radiation therapy system for brachytherapy of breast cancer: results from an international phase II trial.MammoSite放射治疗系统用于乳腺癌近距离放射治疗的临床经验:一项国际II期试验的结果
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Preliminary results and evaluation of MammoSite balloon brachytherapy for partial breast irradiation for pure ductal carcinoma in situ: a phase II clinical study.MammoSite球囊近距离放射治疗纯导管原位癌局部乳腺照射的初步结果与评估:一项II期临床研究。
Am J Surg. 2006 Oct;192(4):427-33. doi: 10.1016/j.amjsurg.2006.06.013.
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Early European experience with the MammoSite radiation therapy system for partial breast brachytherapy following breast conservation operation in low-risk breast cancer.早期欧洲使用MammoSite放射治疗系统对低风险乳腺癌保乳术后进行部分乳腺近距离放射治疗的经验。
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Review of MammoSite brachytherapy: advantages, disadvantages and clinical outcomes.MammoSite近距离放射治疗综述:优点、缺点及临床结果
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Radiation options for early stage breast cancer.早期乳腺癌的放疗选择。
Semin Oncol Nurs. 2006 Nov;22(4):233-41. doi: 10.1016/j.soncn.2006.07.005.
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Advances in radiation treatment of patients with breast cancer.乳腺癌患者放射治疗的进展
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Acute toxicity of high-dose-rate intracavitary brachytherapy with the MammoSite applicator in patients with early-stage breast cancer.使用MammoSite施源器对早期乳腺癌患者进行高剂量率腔内近距离放射治疗的急性毒性
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