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乳腺癌患者放射治疗的进展

Advances in radiation treatment of patients with breast cancer.

作者信息

Gordils-Perez Janet, Rawlins-Duell Robin, Kelvin Joanne Frankel

出版信息

Clin J Oncol Nurs. 2003 Nov-Dec;7(6):629-36. doi: 10.1188/03.CJON.629-636.

DOI:10.1188/03.CJON.629-636
PMID:14705477
Abstract

Breast cancer is the most commonly diagnosed cancer among women in the United States. Approximately half of all patients diagnosed with early-stage breast cancer receive conservative breast surgery followed by consolidative radiation treatment. A number of technologic advances have been made in radiation therapy planning and treatment that minimize early and late toxicities and may improve treatment outcomes. Among these are (a) the treatment of patients with large or pendulous breasts or cardiopulmonary disease in the prone position, (b) intensity-modulated radiation treatment, which delivers precise, highly conformal radiation dose distributions within the breast by using computerized inverse treatment planning and intensity-modulated radiation beams to produce the required dose distribution, and (c) brachytherapy, which is the placement of a radioactive source within the lumpectomy bed. These advances are gaining national recognition and are available at many institutions. Nurses play a vital role in educating patients; therefore, nurses must have the information they need to inform their patients about these advances. The information in this article will allow nurses to help patients understand the anticipated treatment and related side effects and make informed decisions.

摘要

乳腺癌是美国女性中最常被诊断出的癌症。在所有被诊断为早期乳腺癌的患者中,约有一半接受了保乳手术,随后进行巩固性放射治疗。放射治疗计划和治疗方面已经取得了许多技术进步,这些进步将早期和晚期毒性降至最低,并可能改善治疗效果。其中包括:(a)对乳房较大或下垂或患有心肺疾病的患者采用俯卧位治疗;(b)调强放射治疗,通过使用计算机逆向治疗计划和调强放射束在乳房内提供精确、高度适形的放射剂量分布,以产生所需的剂量分布;(c)近距离放射治疗,即将放射源放置在肿块切除腔内。这些进展正在获得全国认可,并且许多机构都可以提供。护士在教育患者方面起着至关重要的作用;因此,护士必须掌握所需信息,以便向患者介绍这些进展。本文中的信息将使护士能够帮助患者了解预期的治疗方法和相关副作用,并做出明智的决定。

相似文献

1
Advances in radiation treatment of patients with breast cancer.乳腺癌患者放射治疗的进展
Clin J Oncol Nurs. 2003 Nov-Dec;7(6):629-36. doi: 10.1188/03.CJON.629-636.
2
Five-year results: the initial clinical trial of MammoSite balloon brachytherapy for partial breast irradiation in early-stage breast cancer.五年结果:MammoSite球囊近距离放射疗法用于早期乳腺癌局部乳腺照射的初步临床试验
Am J Surg. 2007 Oct;194(4):456-62. doi: 10.1016/j.amjsurg.2007.06.010.
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Advances in brachytherapy: new approaches to target breast cancer.近距离放射治疗的进展:针对乳腺癌的新方法
Clin J Oncol Nurs. 2003 May-Jun;7(3):324-8. doi: 10.1188/03.CJON.324-328.
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Radiation therapy. Recent advances and nursing implications.放射治疗。最新进展及护理要点。
Nurs Clin North Am. 1990 Jun;25(2):309-29.
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Early and late skin reactions to radiotherapy for breast cancer and their correlation with radiation-induced DNA damage in lymphocytes.乳腺癌放疗的早期和晚期皮肤反应及其与淋巴细胞中辐射诱导的DNA损伤的相关性。
Breast Cancer Res. 2005;7(5):R690-8. doi: 10.1186/bcr1277. Epub 2005 Jul 1.
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Radiation options for early stage breast cancer.早期乳腺癌的放疗选择。
Semin Oncol Nurs. 2006 Nov;22(4):233-41. doi: 10.1016/j.soncn.2006.07.005.
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Dosimetric analysis of a simplified intensity modulation technique for prone breast radiotherapy.俯卧位乳腺癌放疗简化调强技术的剂量学分析
Int J Radiat Oncol Biol Phys. 2004 Sep 1;60(1):95-102. doi: 10.1016/j.ijrobp.2004.02.016.
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Early European experience with the MammoSite radiation therapy system for partial breast brachytherapy following breast conservation operation in low-risk breast cancer.早期欧洲使用MammoSite放射治疗系统对低风险乳腺癌保乳术后进行部分乳腺近距离放射治疗的经验。
Breast. 2006 Jun;15(3):319-25. doi: 10.1016/j.breast.2006.05.002.
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Partial breast irradiation with interstitial 60CO brachytherapy results in frequent grade 3 or 4 toxicity. Evidence based on a 12-year follow-up of 70 patients.采用60钴组织间近距离放射疗法进行部分乳腺照射会导致频繁出现3级或4级毒性反应。这是基于对70名患者进行12年随访得出的证据。
Int J Radiat Oncol Biol Phys. 2004 Mar 15;58(4):1022-33. doi: 10.1016/j.ijrobp.2003.08.013.
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Radiotherapy confined to the tumor bed following breast conserving surgery current status, controversies, and future projects.保乳手术后局限于瘤床的放疗:现状、争议及未来规划
Strahlenther Onkol. 2002 Nov;178(11):597-606. doi: 10.1007/s00066-002-0966-z.

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Mol Clin Oncol. 2020 Jan;12(1):89-93. doi: 10.3892/mco.2019.1948. Epub 2019 Nov 11.
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Experiences of the Breast Cancer Patients Undergoing Radiotherapy at a Public Hospital Peshawar Pakistan.巴基斯坦白沙瓦一家公立医院乳腺癌患者的放疗经历。
Asia Pac J Oncol Nurs. 2018 Apr-Jun;5(2):184-194. doi: 10.4103/apjon.apjon_70_17.