Aebli N, Krebs J, Schwenke D, Stich H, Schawalder P, Theis J C
Department of Orthopaedic Surgery, University of Otago, Dunedin, New Zealand.
J Bone Joint Surg Br. 2003 May;85(4):499-503. doi: 10.1302/0301-620x.85b4.13605.
We carried out a histological study of a proximally hydroxyapatite (HA)-coated femoral component, retrieved after 9.5 years of good function. The HA coating had completely degraded. Bone was in direct contact with the titanium surface in all the areas which had been coated, with no interposing fibrous tissue. There were no signs of particles, third-body wear, adverse tissue reactions or osteolysis. Bone remodelling was evident by the presence of resorption lacunae; tetracycline labelling showed bone laid down six years after implantation. The loss of the HA-coating had no negative effect on the osseo-integration of the stem. We conclude that the HA coating contributes to the fixation of the implant and that its degradation does not adversely affect the long-term fixation.
我们对一个功能良好达9.5年后取出的近端羟基磷灰石(HA)涂层股骨部件进行了组织学研究。HA涂层已完全降解。在所有曾被涂层覆盖的区域,骨与钛表面直接接触,没有中间纤维组织。没有颗粒、三体磨损、不良组织反应或骨溶解的迹象。通过吸收陷窝的存在可明显看出骨重塑;四环素标记显示植入后六年有新骨形成。HA涂层的丧失对柄的骨整合没有负面影响。我们得出结论,HA涂层有助于植入物的固定,并且其降解不会对长期固定产生不利影响。