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采用颊黏膜移植片构建新阴道。

Neovaginal construction with buccal mucosal grafts.

作者信息

Yeşim Ozgenel Güzin, Ozcan Mesut

机构信息

Department of Plastic and Reconstructive Surgery, Uludağ University, Bursa, Turkey.

出版信息

Plast Reconstr Surg. 2003 Jun;111(7):2250-4. doi: 10.1097/01.PRS.0000060088.19246.05.

DOI:10.1097/01.PRS.0000060088.19246.05
PMID:12794467
Abstract

Several surgical techniques have been designed to construct a neovagina that will be satisfying in appearance, function, and feeling when the vagina is congenitally absent. However, no method has yet been approved as a perfect solution. With the aim of solving the problems with conventional methods, the authors describe a new surgical technique that is simple and safe for treating vaginal agenesis. This technique consists of creating a mucosal lining of the neovaginal cavity using multiple full-thickness buccal mucosal patch grafts. Four patients with congenital absence of the vagina treated with this technique are presented. This surgical procedure created a mucus-providing lining inside the neovagina. Selecting the donor site in the oral region resulted in an inconspicuous donor-site scar. Histologically, the neovaginal lining was confirmed as mucosal, and the cream-colored viscous fluid found in the neovaginal cavity was confirmed as mucus. At a mean follow-up period of 15 months, the neovagina remained adequate in depth and width. All of the patients were interviewed to evaluate the function of the neovagina. Each patient reported having regular sexual intercourse and that the neovagina had felt normal to their partners. The encouraging results obtained in four cases suggest that this new technique deserves further application.

摘要

已经设计了几种手术技术来构建先天性无阴道时外观、功能和感觉均令人满意的新阴道。然而,尚无方法被批准为完美解决方案。为了解决传统方法存在的问题,作者描述了一种治疗阴道发育不全简单且安全的新手术技术。该技术包括使用多个全层颊黏膜补片移植来创建新阴道腔的黏膜内衬。本文介绍了4例采用该技术治疗先天性无阴道的患者。该手术在新阴道内创建了一个分泌黏液的内衬。选择口腔区域作为供区,供区瘢痕不明显。组织学检查证实新阴道内衬为黏膜组织,新阴道腔内发现的米色黏性液体被证实为黏液。平均随访15个月时,新阴道深度和宽度仍足够。对所有患者进行访谈以评估新阴道的功能。每位患者均报告能进行正常性交,且其伴侣感觉新阴道正常。4例患者获得的令人鼓舞的结果表明,这项新技术值得进一步应用。

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引用本文的文献

1
Tissue Options for Construction of the Neovaginal Canal in Gender-Affirming Vaginoplasty.性别确认阴道成形术中用于构建新阴道管的组织选择
J Clin Med. 2024 May 8;13(10):2760. doi: 10.3390/jcm13102760.
2
Vaginoplasty with an Autologous Buccal Mucosa Fenestrated Graft in Two Patients with Vaginal Agenesis: A Multidisciplinary Approach and Literature Review.两名阴道发育不全患者采用自体带孔颊黏膜移植进行阴道成形术:多学科方法及文献综述
J Minim Invasive Gynecol. 2017 May-Jun;24(4):670-676. doi: 10.1016/j.jmig.2016.12.030. Epub 2017 Feb 15.
3
The use of autologous buccal mucosa grafts in vaginal reconstruction.
自体颊黏膜移植在阴道重建中的应用。
Curr Urol Rep. 2014 Aug;15(8):428. doi: 10.1007/s11934-014-0428-z.
4
Autologous buccal mucosa graft for repair of recurrent rectovaginal fistula.自体颊黏膜移植修复复发性直肠阴道瘘
Pediatr Surg Int. 2014 May;30(5):533-5. doi: 10.1007/s00383-014-3495-9. Epub 2014 Mar 14.