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两名阴道发育不全患者采用自体带孔颊黏膜移植进行阴道成形术:多学科方法及文献综述

Vaginoplasty with an Autologous Buccal Mucosa Fenestrated Graft in Two Patients with Vaginal Agenesis: A Multidisciplinary Approach and Literature Review.

作者信息

Chan Jessica L, Levin Pamela J, Ford Brian P, Stanton David C, Pfeifer Samantha M

机构信息

Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California.

Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

J Minim Invasive Gynecol. 2017 May-Jun;24(4):670-676. doi: 10.1016/j.jmig.2016.12.030. Epub 2017 Feb 15.

DOI:10.1016/j.jmig.2016.12.030
PMID:28212868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5411318/
Abstract

Here we describe the procedure and outcomes of a multidisciplinary approach to vaginoplasty using autologous buccal mucosa fenestrated grafts in 2 patients with vaginal agenesis. This procedure resulted in anatomic success, with a functional neovagina with good vaginal length and caliber and satisfactory sexual function capacity and well-healed buccal mucosa. There were no complications, and the patients were satisfied with the surgical results. We conclude that the use of a single fenestrated graft of autologous buccal mucosa is a simple, effective procedure for the treatment of vaginal agenesis that results in an optimally functioning neovagina with respect to vaginal length, caliber, and sexual capacity.

摘要

在此,我们描述了对2例阴道发育不全患者采用多学科方法使用自体带孔颊黏膜进行阴道成形术的过程及结果。该手术取得了解剖学成功,形成了具有良好阴道长度和管径、性功能能力令人满意且颊黏膜愈合良好的功能性新阴道。未出现并发症,患者对手术结果满意。我们得出结论,使用单一的自体带孔颊黏膜移植物是治疗阴道发育不全的一种简单、有效的方法,能形成在阴道长度、管径和性功能方面功能最佳的新阴道。

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本文引用的文献

1
The use of autologous buccal mucosa grafts in vaginal reconstruction.自体颊黏膜移植在阴道重建中的应用。
Curr Urol Rep. 2014 Aug;15(8):428. doi: 10.1007/s11934-014-0428-z.
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An update on surgical and non-surgical treatments for vaginal hypoplasia.阴道发育不全的手术和非手术治疗进展。
Hum Reprod Update. 2014 Sep-Oct;20(5):775-801. doi: 10.1093/humupd/dmu024. Epub 2014 Jun 3.
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Long-term outcomes of vaginoplasty with autologous buccal micromucosa.自体颊部微小黏膜阴道成形术的长期疗效
Obstet Gynecol. 2014 May;123(5):951-956. doi: 10.1097/AOG.0000000000000161.
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Autologous buccal mucosa graft augmentation for foreshortened vagina.自体颊黏膜移植用于阴道缩短的增容术。
Obstet Gynecol. 2014 May;123(5):947-950. doi: 10.1097/AOG.0000000000000226.
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Vaginoplasty by using amnion graft in patients of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser syndrome.采用羊膜移植对与 Mayer-Rokitansky-Kuster-Hauser 综合征相关的阴道发育不全患者进行阴道成形术。
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Psychosexual and functional outcomes after creation of a neovagina with laparoscopic Davydov in patients with vaginal agenesis.腹腔镜阴道再造术(Davydov 法)治疗阴道闭锁患者的心理性和功能性结局。
Fertil Steril. 2010 Nov;94(6):2272-6. doi: 10.1016/j.fertnstert.2010.02.008. Epub 2010 Mar 16.
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Intestinal vaginoplasty: seven years' experience of a tertiary center.肠阴道成形术:一家三级中心的七年经验。
Fertil Steril. 2010 Nov;94(6):2312-5. doi: 10.1016/j.fertnstert.2010.01.004. Epub 2010 Feb 20.
8
Use of autologous micromucosa graft for vaginoplasty in vaginal agenesis.自体微小黏膜移植在先天性无阴道阴道成形术中的应用。
Ann Plast Surg. 2009 Dec;63(6):645-9. doi: 10.1097/SAP.0b013e31819adfab.
9
Should progressive perineal dilation be considered first line therapy for vaginal agenesis?渐进性会阴扩张术应被视为阴道发育不全的一线治疗方法吗?
J Urol. 2009 Oct;182(4 Suppl):1882-9. doi: 10.1016/j.juro.2009.03.071. Epub 2009 Aug 20.
10
Functional and anatomic results of amnion vaginoplasty in young women with Mayer-Rokitansky-Küster-Hauser syndrome.Mayer-Rokitansky-Küster-Hauser 综合征年轻女性行羊膜阴道成形术后的功能和解剖学结果。
Fertil Steril. 2010 Jun;94(1):317-23. doi: 10.1016/j.fertnstert.2009.01.154. Epub 2009 Mar 27.