Schwartz Lawrence H, Lefkowitz Robert A, Panicek David M, Coakley Fergus V, Jarnagin William, Dematteo Ronald, Fong Yuman, Blumgart Leslie
Department of Radiology, Memmorial Sloan - Kettering Cancer Center, and Weill Medical College of Cornell University, New York, NY 10021, USA.
J Comput Assist Tomogr. 2003 May-Jun;27(3):307-14. doi: 10.1097/00004728-200305000-00002.
This study was designed to determine the effectiveness of magnetic resonance cholangiopancreatography (MRCP) using a breath-hold single-shot fast spin echo (SSFSE) technique in imaging patients with malignant biliary and/or pancreatic duct obstruction.
One hundred thirty-one breath-hold MRCP studies in patients with malignant pancreatic and/or biliary obstruction were evaluated. Pathologic diagnoses included pancreatic cancer, biliary malignancy, gallbladder carcinoma, hepatic neoplasms, malignant lymphadenopathy, and ampullary carcinoma. Two observers independently reviewed the images in a blinded fashion to assess the level of obstruction and the site of underlying tumor.
The level of obstruction was correctly identified in 104 of 131 cases (79%) by observer 1 and in 107 of 131 cases (82%) by observer 2. The site of underlying tumor was correctly identified in 113 of 131 cases (86%) by observer 1 and in 110 of 131 cases (84%) by observer 2.
Magnetic resonance cholangiopancreatography utilizing the SSFSE technique can accurately assess the level of obstruction and the site of underlying tumor in patients with malignant pancreaticobiliary obstruction, without the risks of cholangiography. This MRCP technique allows for visualization of intra- and extraductal anatomy and pathology.
本研究旨在确定采用屏气单次激发快速自旋回波（SSFSE）技术的磁共振胰胆管造影（MRCP）在恶性胆管和/或胰管梗阻患者成像中的有效性。
对131例恶性胰腺和/或胆管梗阻患者的屏气MRCP研究进行了评估。病理诊断包括胰腺癌、胆管恶性肿瘤、胆囊癌、肝脏肿瘤、恶性淋巴结病和壶腹癌。两名观察者以盲法独立回顾图像，以评估梗阻水平和潜在肿瘤的部位。
观察者1在131例病例中的104例（79%）中正确识别了梗阻水平，观察者2在131例病例中的107例（82%）中正确识别了梗阻水平。观察者1在131例病例中的113例（86%）中正确识别了潜在肿瘤的部位，观察者2在131例病例中的110例（84%）中正确识别了潜在肿瘤的部位。
利用SSFSE技术的磁共振胰胆管造影可以准确评估恶性胰胆管梗阻患者的梗阻水平和潜在肿瘤的部位，而无胆管造影的风险。这种MRCP技术能够显示导管内和导管外的解剖结构及病理情况。
