Mougenel J L, Hudziak H, Ernst O, Dupas B, Lefevre F, Barraud H, Watelet J, Cezard O, Regent D, Bigard M A
Service d'Hépato-Gastroentérologie, CHU Nancy.
Gastroenterol Clin Biol. 2000 Oct;24(10):888-95.
To assess the accuracy and reproducibility of a new magnetic resonance cholangiopancreatography sequence (MRCP), using long echo time and "single shot" acquisition (providing high-contrast thick slices: 20 mm or more), in the morphological analysis of the biliary tree and pancreatic ducts.
Fifty four patients with biliary and/or pancreatic disease were investigated with MRCP "single shot" thick slices. Biliary ducts were explored with MRCP "single shot", coronal and oblique coronal 20 mm thick slices on a 256 x 256 matrix. Natives pictures were reviewed by three independent radiologists, from three different institutions. MRCP results were compared with reference examinations in 54 cases (direct biligraphy methods: 54, CT scan: 11, endoscopic ultrasonography: 6, surgery: 6).
For detection of bile duct dilatation, the agreement of MRCP "single shot" thick slices was more than 96% (Kappa > 0.92) and the inter-observer agreement was excellent (Kappa=0.92). For detection of biliary tree and/or pancreatic duct obstruction, MRCP "single shot" thick slice sensitivity was above 89% and specificity was 75%. The malignant nature of the lesions was determined with a sensitivity of 100% and a specificity of 92%. MRCP "single shot" thick slices could not differentiate pancreatic carcinomas from distal main bile duct cholangiocarcinomas. MRCP "single shot" thick slices did not detect small stones ( 3 mm) of the common bile duct.
The excellent sensitivity, specificity and inter-observer agreement of MRCP "single shot" thick slices can be used to limit invasive imaging methods in the diagnosis of extrahepatic cholestasis.
评估一种新的磁共振胰胆管造影序列(MRCP)的准确性和可重复性,该序列采用长回波时间和“单次激发”采集(提供高对比度厚层图像:20毫米或更厚),用于胆管树和胰管的形态学分析。
对54例患有胆管和/或胰腺疾病的患者进行了MRCP“单次激发”厚层图像检查。使用MRCP“单次激发”,在256×256矩阵上获取冠状位和斜冠状位20毫米厚的胆管图像。来自三个不同机构的三位独立放射科医生对原始图像进行了评估。将54例患者的MRCP结果与参考检查结果进行了比较(直接胆道造影方法:54例,CT扫描:11例,内镜超声检查:6例,手术:6例)。
对于胆管扩张的检测,MRCP“单次激发”厚层图像的一致性超过96%(Kappa>0.92),观察者间一致性极佳(Kappa=0.92)。对于胆管树和/或胰管梗阻的检测,MRCP“单次激发”厚层图像的敏感性高于89%,特异性为75%。病变的恶性性质诊断敏感性为100%,特异性为92%。MRCP“单次激发”厚层图像无法区分胰腺癌和远端肝外胆管癌。MRCP“单次激发”厚层图像未检测到胆总管内直径小于3毫米的小结石。
MRCP“单次激发”厚层图像具有出色的敏感性、特异性和观察者间一致性,可用于限制肝外胆汁淤积诊断中侵入性成像方法的使用。