Firstenberg M S, Greenberg N L, Garcia M J, Castro P L, Prior D L, Smedira N G, Thomas J D
The Cardiovascular Imaging Center, The Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Comput Cardiol. 1999;26:181-4.
We hypothesize that a simplified version of the Euler equation (SEE) utilizing differences in velocity over a distance and time as obtained by Color Doppler M-mode (CMM) echocardiography can approximate actual peak transmitral pressure gradients deltaP(TM).
In 14 patients undergoing open-heart surgery, deltaP(TM) was measured under various hemodynamic conditions using 2 high fidelity transducers, 5 cm apart. Transesophageal CMM images were simultaneously acquired and a customized image analysis application was used to abstract spatiotemporal velocity characteristics. Using both the SEE and a simplified Bernoulli equations, deltaP(TM) were determined and compared to the actual deltaP(TM).
While the simplified Bernoulli equation resulted in a poor estimate (y=0.075x+0.71, r=0.45), the deltaP(TM) obtained using the SEE correlated strongly (y=0.79x+0.48, r=0.91) with the actual measurements.
Semi-automated analysis of CMM images using a SEE can accurately estimate actual deltaP(TM).
我们假设，利用彩色多普勒M型（CMM）超声心动图获取的距离和时间上的速度差异的欧拉方程简化版（SEE）可以近似实际的二尖瓣峰值压力阶差ΔP（TM）。
在14例接受心脏直视手术的患者中，使用两个相距5厘米的高保真换能器在各种血流动力学条件下测量ΔP（TM）。同时采集经食管CMM图像，并使用定制的图像分析应用程序提取时空速度特征。使用SEE和简化的伯努利方程确定ΔP（TM），并将其与实际的ΔP（TM）进行比较。
虽然简化的伯努利方程估计效果较差（y = 0.075x + 0.71，r = 0.45），但使用SEE获得的ΔP（TM）与实际测量值高度相关（y = 0.79x + 0.48，r = 0.91）。
使用SEE对CMM图像进行半自动分析可以准确估计实际的ΔP（TM）。
