Mirsattari Seyed M, Lee Donald H, Jones Michael W, Blume Warren T
Department of Clinical Neurological Sciences, University of Western Ontario, Canada.
Neurology. 2003 Jun 10;60(11):1838-41. doi: 10.1212/01.wnl.0000058754.99940.11.
Pathogenesis of a rarely occurring transient, isolated focal lesion of the splenium of the corpus callosum in epilepsy patients is uncertain: frequent seizures or antiepileptic drug reduction causing ischemia or demyelination is possible. The several MRI sequences, including diffusion-weighted imaging, in this first case of occipital epilepsy suggest ischemia from rapid carbamazepine reduction, frequent seizures, or a combination of both.
癫痫患者胼胝体压部罕见的短暂性、孤立性局灶性病变的发病机制尚不确定：频繁发作或抗癫痫药物减量导致缺血或脱髓鞘是有可能的。在这例首例枕叶癫痫病例中，包括弥散加权成像在内的多种MRI序列提示，卡马西平快速减量、频繁发作或两者共同作用导致了缺血。
