一名儿童患混合型无性细胞瘤，血清中人绒毛膜促性腺激素和甲胎蛋白浓度均高。

A case of mixed-type dysgerminoma with a high serum concentration of both human chorionic gonadotropin and alpha-fetoprotein in a child.

作者信息

Uno T, Harada Y, Hongo T, Fujii Y, Hashimoto R, Kawarazaki H

机构信息

First Department of Surgery, Hamamatsu University School of Medicine, Japan.

出版信息

Acta Paediatr Jpn. 1992 Oct;34(5):558-62. doi: 10.1111/j.1442-200x.1992.tb01008.x.

DOI:10.1111/j.1442-200x.1992.tb01008.x

PMID:1279935

Abstract

Dysgerminoma is divided into two types: pure and mixed. The mixed type is related to other various elements of germ cell tumors. We experienced a case of mixed type dysgerminoma with a high serum concentration of both human chorionic gonadotropin and alpha-fetoprotein. The patient was a 6 year old girl who was admitted to the Hamamatsu University School of Medicine with an abdominal mass. Laboratory investigations revealed elevated serum alpha-fetoprotein and high concentration of serum beta-human chorionic gonadotropin. The tumor originated from the left ovary. The histopathological diagnosis was dysgerminoma. Serum human chorionic gonadotropin and alpha-fetoprotein levels were useful markers in monitoring the response to treatment in this patient.

摘要

无性细胞瘤分为两种类型

纯型和混合型。混合型与生殖细胞肿瘤的其他各种成分有关。我们遇到了一例混合型无性细胞瘤患者，其血清中人绒毛膜促性腺激素和甲胎蛋白的浓度都很高。该患者是一名6岁女孩，因腹部肿块入住滨松医科大学。实验室检查显示血清甲胎蛋白升高，血清β-人绒毛膜促性腺激素浓度很高。肿瘤起源于左侧卵巢。组织病理学诊断为无性细胞瘤。血清人绒毛膜促性腺激素和甲胎蛋白水平是监测该患者治疗反应的有用标志物。