Andersen Johan Hviid, Thomsen Jane Froelund, Overgaard Erik, Lassen Christina Funch, Brandt Lars Peter Andreas, Vilstrup Imogen, Kryger Ann Isabel, Mikkelsen Sigurd
Department of Occupational Medicine, Herning Hospital, Herning, Denmark.
JAMA. 2003 Jun 11;289(22):2963-9. doi: 10.1001/jama.289.22.2963.
Computer use is increasingly common among many working populations, and concern exists about possible adverse effects of computer use, such as carpal tunnel syndrome (CTS).
To estimate the prevalence and incidence of possible CTS and to evaluate the contribution of use of mouse devices and keyboards to the risk of possible CTS.
A 1-year follow-up study with questionnaires conducted in 2000 and 2001 at 3500 workplaces in Denmark, followed on each of the 2 occasions by a clinical interview on symptom distribution and frequency.
The questionnaire was sent to 9480 members of a trade union, with an initial response rate of 73% (n = 6943), and 82% (n = 5658) at follow-up.
At baseline, there were 3 outcome measures: tingling/numbness in the right hand once a week or more as reported in the questionnaire; tingling, numbness, and pain in the median nerve in the right hand confirmed by clinical interview; and tingling, numbness, and pain in the median nerve in the right hand at night confirmed by clinical interview. At 1 year of follow-up the main outcome of interest was onset of symptoms among participants who had no or minor symptoms at baseline.
The overall self-reported prevalence of tingling/numbness in the right hand at baseline was 10.9%. The interview confirmed that prevalence of tingling/numbness in the median nerve was 4.8%, of which about one third, corresponding to a prevalence of 1.4%, experienced symptoms at night. Onset of new symptoms in the 1-year follow-up was 5.5%. In the cross-sectional comparisons and in the follow-up analyses, there was an association between use of a mouse device for more than 20 h/wk and risk of possible CTS but no statistically significant association with keyboard use.
The occurrence of possible CTS in the right hand was low. The study emphasizes that computer use does not pose a severe occupational hazard for developing symptoms of CTS.
在许多工作人群中，使用计算机越来越普遍，人们担心使用计算机可能产生的不良影响，如腕管综合征（CTS）。
估计可能患CTS的患病率和发病率，并评估使用鼠标设备和键盘对可能患CTS风险的影响。
2000年和2001年在丹麦3500个工作场所进行了一项为期1年的随访研究，通过问卷调查，并在每次调查后进行关于症状分布和频率的临床访谈。
向一个工会的9480名成员发放问卷，初始回复率为73%（n = 6943），随访时的回复率为82%（n = 5658）。
在基线时，有3项观察指标：问卷中报告右手每周出现一次或更多次刺痛/麻木；临床访谈确认右手正中神经出现刺痛、麻木和疼痛；临床访谈确认右手正中神经在夜间出现刺痛、麻木和疼痛。在随访1年时，主要关注的观察指标是基线时无或有轻微症状的参与者出现症状。
基线时右手自我报告的刺痛/麻木总体患病率为10.9%。临床访谈确认正中神经刺痛/麻木的患病率为4.8%，其中约三分之一，即患病率为1.4%的人在夜间出现症状。1年随访中新症状的发生率为5.5%。在横断面比较和随访分析中，每周使用鼠标设备超过20小时与可能患CTS的风险之间存在关联，但与键盘使用无统计学显著关联。
右手可能患CTS的发生率较低。该研究强调，使用计算机不会对CTS症状的发展构成严重职业危害。
