对从患有各种形式阴道念珠菌病的女性中分离出的白色念珠菌菌株的研究。

Study of Candida albicans strains isolated from women with various forms of vaginal candidiasis.

作者信息

Nikitin M V, Artemova L V, Kravtsov E G, Dalin M V, Radzinskii V E, Doyle R J

机构信息

Russian University of Peoples' Friendship, Moscow.

出版信息

Bull Exp Biol Med. 2003 Mar;135(3):276-80. doi: 10.1023/a:1024145300447.

DOI:10.1023/a:1024145300447

PMID:12802401

Abstract

Adhesive activity of Candida albicans towards vaginal epitheliocytes is hormone-dependent. Two types of C. albicans adhesins sensitive to polyphenyloxidase and asparaginase were detected. Laser irradiation nonspecifically modulated both adhesin types. Population relationships between fungi and lactobacilli in patients with vaginal candidal infection and in C. albicans carriers were studied. Genodiagnostic method for identification of C. albicans and morphogenesis-associated genes of these yeast-like fungi was approved.

摘要

白色念珠菌对阴道上皮细胞的黏附活性是激素依赖性的。检测到两种对多酚氧化酶和天冬酰胺酶敏感的白色念珠菌黏附素。激光照射对两种黏附素均产生非特异性调节作用。研究了阴道念珠菌感染患者及白色念珠菌携带者中真菌与乳酸杆菌的种群关系。批准了用于鉴定白色念珠菌及其这些酵母样真菌形态发生相关基因的基因诊断方法。