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女性性激素对白色念珠菌酵母样真菌黏附于颊黏膜上皮的影响。

Effects of female sex hormones on adhesion of Candida albicans yeast-like fungi to the buccal epithelium.

作者信息

Kravtsov E G, Anokhina I V, Rybas Ya A, Sachivkina N P, Ermolaev A V, Brodskaya S B

机构信息

Department of Microbiology and Virology, Medical Faculty, Peoples' Friendship University of Russia, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2014 Jun;157(2):246-8. doi: 10.1007/s10517-014-2536-7. Epub 2014 Jun 24.

Abstract

Hormonal regulation of receptor expression and glycogen concentrations in the epithelial cells of the oral cavity remains poorly studied. Adhesion of microorganisms to the vaginal epithelium correlates with their adhesion to the buccal epithelium. Analysis of the correlation between Candida adhesion to the vaginal and buccal epithelium depending on the hormonal status has demonstrated that activity of Candida albicans strains in the buccal epithelium correlates with their adhesion activity in the vaginal epithelium, with the coefficient of correlations (r) reaching 0.76.

摘要

口腔上皮细胞中受体表达和糖原浓度的激素调节仍研究不足。微生物与阴道上皮的黏附与其与颊上皮的黏附相关。对念珠菌在阴道和颊上皮的黏附与激素状态之间的相关性分析表明,白色念珠菌菌株在颊上皮中的活性与其在阴道上皮中的黏附活性相关,相关系数(r)达0.76。

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