Kuvaki B, Gökmen N, Günenç F, Ceyhan Kara H, Uzümlü H, Ozden G, Söylev M, Gökel E
Department of Anaesthesiology, Dokuz Eylül University Medical School, Izmir, Turkey.
Acta Anaesthesiol Scand. 2003 Jul;47(6):739-41. doi: 10.1034/j.1399-6576.2003.00125.x.
Retrobulbar injection can be associated with significant pain, due to both needle insertion and deposition of the local anaesthetic solution. The local anaesthetic cream EMLA (eutectic mixture of local anaesthetics) which contains a mixture of lignocaine and prilocaine has been shown to reduce the pain associated with skin puncture. The efficacy of EMLA in alleviating the pain of retrobulbar injection for cataract surgery was assessed in this study.
In this, randomised double-blind study, EMLA (n = 53) or lignocaine 5% ointment (n = 50) was administered to the inferior orbital margin at least 45 min before retrobulbar block in 103 patients. Pain assessed during retrobulbar block was marked subjectively by the patient on a 10-point numerical rating scale.
Median verbal pain scores were 3.0 with an interquartile range of 1.5-6.5 in the control group and 3.50 with an interquartile range of 2.0-6.0 in the EMLA(R) group (P = 0.67). There was no significant difference between the EMLA group and the lignocaine ointment group according to this pain assessment.
EMLA does not permit pain-free retrobulbar injection.
球后注射可能会伴有明显疼痛,这是由针头插入以及局部麻醉溶液的注射所导致的。含有利多卡因和丙胺卡因混合物的局部麻醉乳膏EMLA(局部麻醉药的共熔混合物)已被证明可减轻与皮肤穿刺相关的疼痛。本研究评估了EMLA在减轻白内障手术球后注射疼痛方面的疗效。
在这项随机双盲研究中,103例患者在球后阻滞前至少45分钟在下眼眶缘涂抹EMLA(n = 53)或5%利多卡因软膏(n = 50)。患者在球后阻滞期间所感受到的疼痛通过10分数字评分量表进行主观评分。
对照组的语言疼痛评分中位数为3.0,四分位间距为1.5 - 6.5;EMLA组的语言疼痛评分中位数为3.50,四分位间距为2.0 - 6.0(P = 0.67)。根据该疼痛评估,EMLA组与利多卡因软膏组之间无显著差异。
EMLA不能实现无痛球后注射。