Pappa X, Pouliou K, Nastou H, Dovinou K, Stamatiou I
Department of Anaesthesiology A Fleming Hospital Melissa, Athens, Greece.
Acta Anaesthesiol Belg. 1995;46(2):75-8.
In an observer blind study, the efficacy of lignocaine-prilocaine eutectic mixture was established in alleviating the pain of needle insertion during retrobulbar and periorbital tissues block in cataract surgery. Thirty-three patients were allocated randomly into two groups. Patients in group 1 (n = 17) received EMLA cream 60 min. prior to local anesthesia while those of group 2 (n = 16) were used as a control group. Pain was graded by the patients on a four-point verbal rating scale (VRS) as well as by an observer, unaware of the treatment patients received, on a 4-point scale. In both groups there were no differences in pain scores between patient's and observer's assessments. In EMLA group significantly (p < 0.05) less pain was registered during performance of the local anesthetic procedure. Our results demonstrate that the eutectic mixture may be very effective in reducing pain associated with locoregional procedures for eye surgery.
在一项观察者盲法研究中,证实了利多卡因-丙胺卡因共熔混合物在减轻白内障手术球后和眶周组织阻滞时的进针疼痛方面的疗效。33例患者被随机分为两组。第1组(n = 17)的患者在局部麻醉前60分钟使用EMLA乳膏,而第2组(n = 16)的患者作为对照组。患者根据四点口头评定量表(VRS)对疼痛进行分级,同时由不知道患者接受何种治疗的观察者根据四点量表进行分级。两组患者和观察者的评估之间疼痛评分均无差异。在EMLA组,局部麻醉操作过程中记录到的疼痛明显较少(p < 0.05)。我们的结果表明,共熔混合物在减轻与眼部手术局部区域操作相关的疼痛方面可能非常有效。