Zaccagna Alessandro, Bertone Alberto, Puiatti Paolo, Picciotto Franco, Sprujevnik Tatiana, Santucci Renato, Rossini Francesco Paolo
Institute for Cancer Research and Treatment (IRCC), Operative Unit of Dermatologic Surgery, Str.Prov.142, Km 3.95, 10060 Candiolo, Italy.
Eur J Dermatol. 2003 May-Jun;13(3):258-60.
Here we report a case of Pyoderma gangrenosum (PG) associated with Crohn's disease successfully treated with infliximab. The efficacy of this drug in many inflammatory diseases has already been reported, but its use in PG has only been seen in very few cases. Our study confirms that this therapy is a valid alternative solution for treating PG, which is often unresponsive to conventional therapies.
在此,我们报告一例用英夫利昔单抗成功治疗的与克罗恩病相关的坏疽性脓皮病(PG)病例。该药物在许多炎症性疾病中的疗效已有报道,但其在PG中的应用仅见于极少数病例。我们的研究证实,这种疗法是治疗PG的一种有效的替代解决方案,PG通常对传统疗法无反应。