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[一名养猪户感染猪链球菌引起的化脓性脑膜炎]

[Purulent meningitis caused by Streptococcus suis in a pig breeder].

作者信息

Matsuo Hirosuke, Sakamoto Seizaburou

机构信息

Central Laboratory, Sasebo Chuo Hospital.

出版信息

Kansenshogaku Zasshi. 2003 May;77(5):340-2. doi: 10.11150/kansenshogakuzasshi1970.77.340.

DOI:10.11150/kansenshogakuzasshi1970.77.340
PMID:12806930
Abstract

A case of Purulent meningitis caused by Streptococcus suis type 2 is reported here. It occurred in a 58-year-old male pig breeder. A few days before presentation, the patient had experienced headache, systemic articular pain and fever (38.8 degrees C). On admission, he was stuporous and had neck stiffness and hemiparesis. Examination of cerebrospinal fluid showed purulent meningitis. The cultures identified Streptococcus suis II by PCR and specific serum. 2 months later, the patient was discharged in good clinical condition except for hearing loss. Streptococcus suis is known to be an important pathogen in the swine industry, this report is the first case of S. suis meningitis in man, in Japan.

摘要

本文报告一例由2型猪链球菌引起的化脓性脑膜炎病例。患者为一名58岁的男性养猪户。发病前几天,患者出现头痛、全身关节疼痛和发热(38.8摄氏度)。入院时,患者昏迷,有颈部僵硬和偏瘫症状。脑脊液检查显示为化脓性脑膜炎。通过聚合酶链反应(PCR)和特异性血清培养鉴定出猪链球菌II型。2个月后,患者临床状况良好出院,但有听力损失。猪链球菌是养猪业中的一种重要病原体,本报告是日本首例人类感染猪链球菌脑膜炎病例。

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引用本文的文献

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Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing.猪链球菌,一种重要的猪病原体和新出现的人畜共患病原体——基于血清型和序列分型的全球分布最新情况
Emerg Microbes Infect. 2014 Jun;3(6):e45. doi: 10.1038/emi.2014.45. Epub 2014 Jun 18.
2
Molecular characterization of Streptococcus suis strains by 16S-23S intergenic spacer polymerase chain reaction and restriction fragment length polymorphism analysis.用16S-23S基因间隔区聚合酶链反应和限制性片段长度多态性分析对猪链球菌菌株进行分子特征鉴定
Can J Vet Res. 2006 Apr;70(2):94-104.
3
Multiplex PCR assay for detection of Streptococcus suis species and serotypes 2 and 1/2 in tonsils of live and dead pigs.
用于检测生猪和死猪扁桃体中猪链球菌种类以及2型和1/2型血清型的多重聚合酶链反应检测法
J Clin Microbiol. 2004 Jul;42(7):3169-75. doi: 10.1128/JCM.42.7.3169-3175.2004.