The peripheral generation of CD4+ CD25+ regulatory T cells.
作者信息
Akbar Arne N, Taams Leonie S, Salmon Mike, Vukmanovic-Stejic Milica
机构信息
Department of Immunology and Molecular Pathology, Windeyer Institute for Medical Sciences, Royal Free and University College Medical School, London, UK.
出版信息
Immunology. 2003 Jul;109(3):319-25. doi: 10.1046/j.1365-2567.2003.01678.x.
Abstract
摘要
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Regulatory T cells under scrutiny.受审查的调节性T细胞。
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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.Foxp3对CD4+CD25+调节性T细胞的发育和功能进行编程。
Nat Immunol. 2003 Apr;4(4):330-6. doi: 10.1038/ni904. Epub 2003 Mar 3.
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Control of regulatory T cell development by the transcription factor Foxp3.转录因子Foxp3对调节性T细胞发育的调控
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T cell anergy.T细胞无能
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Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers.外周CD4+ T细胞的稳态：白细胞介素-2受体α和白细胞介素-2塑造了一群调节性细胞，该细胞群控制着CD4+ T细胞的数量。
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Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.人CD4+CD25+调节性T细胞对抗原特异性T细胞的抑制作用。
Eur J Immunol. 2002 Jun;32(6):1621-30. doi: 10.1002/1521-4141(200206)32:6<1621::AID-IMMU1621>3.0.CO;2-Q.
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CD4+ CD25+ suppressor T cells: more questions than answers.CD4+ CD25+ 抑制性T细胞：问题多于答案。
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Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood.人胸腺、脐带血和成人血液中CD25⁺ CD4⁺ T细胞的特征分析
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In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.免疫抑制药物可诱导体外产生白细胞介素10的调节性CD4(+) T细胞，而1型辅助性T细胞（Th1）和2型辅助性T细胞（Th2）诱导细胞因子则会抑制其产生。
J Exp Med. 2002 Mar 4;195(5):603-16. doi: 10.1084/jem.20011629.
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