Lappalainen Reijo, Selenius Mikko, Anttila Asko, Konttinen Yrjö T, Santavirta Seppo S
Department of Applied Physics, University of Kuopio, P.O. Box 1627, FIN-70211 Kuopio, Finland.
J Biomed Mater Res B Appl Biomater. 2003 Jul 15;66(1):410-3. doi: 10.1002/jbm.b.10026.
Wear-debris-induced periprosthetic bone loss and aseptic loosening is regarded as the main long-term problem of total hip replacements (THRs). In this study the amount of wear debris from articulating surfaces of THRs was reduced so as to be close to negligible by the use of high-quality amorphous diamond (AD) coatings deposited by pulsed plasma arc techniques. The wear rates determined in a commercial hip simulator for 15 million walking cycles (corresponding to about 15 years of clinical use) in serum lubrication were even 1,000,000 times lower than the clinical values for conventional THRs (polyethylene-metal or metal-metal pairs). Elimination of wear debris and good biomechanical performance should provide a substantial improvement of the clinical longevity of the THRs.
磨损碎屑引起的假体周围骨丢失和无菌性松动被认为是全髋关节置换术（THR）的主要长期问题。在本研究中，通过使用脉冲等离子弧技术沉积的高质量非晶金刚石（AD）涂层，全髋关节置换术关节表面的磨损碎屑量得以减少，几乎可以忽略不计。在商用髋关节模拟器中测定的血清润滑条件下1500万次行走循环（相当于约15年临床使用）的磨损率，甚至比传统全髋关节置换术（聚乙烯-金属或金属-金属配对）的临床值低100万倍。消除磨损碎屑和良好的生物力学性能应能显著提高全髋关节置换术的临床使用寿命。
