Lim Lynne Hsueh Yee, Chao Siew Shuen, Goh Christopher Hood Keng, Ng Chee Yung, Goh Yau Hong, Khin Lay Wai
Department of Otolaryngology, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
Head Neck. 2003 Jul;25(7):543-8. doi: 10.1002/hed.10267.
To determine the presentation and management of parotid lesions requiring excision in a largely Chinese Asian population.
Retrospective study of 118 consecutive parotidectomies.
Thirty-seven percent were Warthin's tumor (WT), 33% pleomorphic adenoma (PA), 21% other benign disease (OBD), and 9% malignant tumor (MT). Mean age was significantly different between benign (51 years) and malignant (40 years) lesions. MT decreased above 50 years, but increased five times with pain and two times with a noninferior pole lesion. Sensitivity of fine-needle aspiration (FNA) for differentiating benign from MT = 78%, for WT =5 8%, for PA =82%, for OBD = 28%, and for MT = 38%. CT scans did not alter WT management. Facial nerve (FN) paresis was not associated with histology, tumor size, site, or parotidectomy type.
This is the first report documenting that most benign parotid tumors are WT and not PA. MT risk is greater in those less than 50 with pain and a noninferior pole lesion. Cystic lesions such as WT require great care in the evaluation of FNA findings.
确定在以华裔亚洲人为主的人群中需要切除的腮腺病变的表现及处理方式。
对118例连续性腮腺切除术进行回顾性研究。
37%为沃辛瘤(WT),33%为多形性腺瘤(PA),21%为其他良性疾病(OBD),9%为恶性肿瘤(MT)。良性病变(51岁)和恶性病变(40岁)的平均年龄有显著差异。MT在50岁以上患者中减少,但因疼痛而发病的患者中增加了5倍,在下极病变患者中增加了2倍。细针穿刺抽吸活检(FNA)鉴别良性病变与MT的敏感性为78%,鉴别WT为58%,鉴别PA为82%,鉴别OBD为28%,鉴别MT为38%。CT扫描不改变WT的处理方式。面神经(FN)麻痹与组织学、肿瘤大小、部位或腮腺切除类型无关。
这是首份记录表明大多数腮腺良性肿瘤为WT而非PA的报告。年龄小于50岁且伴有疼痛及下极病变的患者发生MT的风险更高。对于WT等囊性病变,评估FNA结果时需格外谨慎。