Kolettis Peter N, Woo Lynn, Sandlow Jay I
Division of Urology, Department of Surgery, University of Alabama at Birmingham School of Medicine, 35294-3296, USA.
Urology. 2003 Jun;61(6):1221-3. doi: 10.1016/s0090-4295(03)00023-2.
To review the fertility outcomes of patients who underwent vasectomy reversal and attempted conception with the same female partners.
A retrospective review of two surgeons' experience was performed. Patency was defined as the presence of motile sperm. Patients with less than 6 months of follow-up were excluded from the patency rate analysis unless they had sperm in the semen sample. Similarly, patients with less than 6 months of follow-up or no ongoing interest in establishing conception were excluded from the pregnancy rate analysis unless they had established a pregnancy.
Of 200 consecutive men, 34 (17%) underwent microsurgical vasectomy reversal with the same female partner. All but two of the couples had previous proven fertility. The procedures performed for those who pursued fertility were bilateral vasovasostomy (n = 27), vasovasostomy/vasoepididymostomy (n = 4), and bilateral vasoepididymostomy (n = 1). The mean obstructive interval was 5 years (range 4 months to 10 years). The mean female partner age was 31.9 years (range 26 to 38). The median follow-up was 8 months (range 1 to 48). Patency was achieved in 27 (93%) of 29, and pregnancy occurred in 15 (60%) of 25 cases with sufficient follow-up. The ongoing or delivered rate was 56% (14 of 25). Female factor problems were present in three couples, and two miscarriages occurred for couples with known female factor problems.
Microsurgical vasectomy reversal may have higher success rates when performed for couples with the same female partner. These results may be related to a shorter obstructive interval and a history of previous fertility as a couple.
回顾接受输精管复通术并与相同女性伴侣尝试受孕的患者的生育结局。
对两位外科医生的经验进行回顾性分析。通畅定义为存在活动精子。随访时间少于6个月的患者被排除在通畅率分析之外,除非其精液样本中有精子。同样,随访时间少于6个月或对受孕无持续意愿的患者被排除在妊娠率分析之外,除非他们已怀孕。
在连续的200名男性中,34名(17%)与相同女性伴侣接受了显微外科输精管复通术。除两对夫妇外,其他夫妇既往均有生育史。为追求生育的患者实施的手术包括双侧输精管吻合术(n = 27)、输精管吻合术/输精管附睾吻合术(n = 4)和双侧输精管附睾吻合术(n = 1)。平均梗阻时间为5年(范围4个月至10年)。女性伴侣的平均年龄为31.9岁(范围26至38岁)。中位随访时间为8个月(范围1至48个月)。29例中有27例(93%)实现通畅,25例有足够随访时间的患者中有15例(60%)怀孕。持续妊娠或分娩率为56%(25例中的14例)。三对夫妇存在女性因素问题,已知有女性因素问题的夫妇发生了两次流产。
为与相同女性伴侣的夫妇进行显微外科输精管复通术可能具有更高的成功率。这些结果可能与较短的梗阻时间以及夫妇既往的生育史有关。