原核生物和低等真核生物中翻译调控机制的多样性。

Diversity of mechanisms in the regulation of translation in prokaryotes and lower eukaryotes.

作者信息

Lindahl L, Hinnebusch A

机构信息

Department of Biology, University of Rochester, New York 14627.

出版信息

Curr Opin Genet Dev. 1992 Oct;2(5):720-6. doi: 10.1016/s0959-437x(05)80132-7.

DOI:10.1016/s0959-437x(05)80132-7

PMID:1281027

Abstract

Regulation of translation is used to control the expression of many essential and highly expressed genes. The known repertoire of molecular mechanisms for translational regulation is expanding. Recently elucidated mechanisms involve alterations in mRNA structure and modulation of the activity of translation initiation factors.

摘要

翻译调控被用于控制许多必需且高表达基因的表达。翻译调控的已知分子机制库正在不断扩展。最近阐明的机制涉及mRNA结构的改变以及翻译起始因子活性的调节。