Gebhardt C, Köhler J, Jurowich C
Klinik für Abdominal-, Thorax- und Endokrine Chirurgie, Klinikum Nuremberg.
Zentralbl Chir. 2003 May;128(5):396-400. doi: 10.1055/s-2003-40035.
Between 1986-1995 we operated 337 patients with ductal adenocarcinoma of the pancreas, 45 cases of carcinoma of the papilla of Vater and 11 patients with cystadenocarcinoma of the pancreas. The evaluation of prognostic factors showed the influence of lymph node invasion. Furthermore we saw a significant influence of lymph- and haemangiosis carcinomatosa, of tumor-grading and tumor-size. The carcinoma of the papilla showed a better 5-year survival even in nodal-positive patients--this as a result of a different biological behaviour. We think that--instead of missing improvement of cure in ductal adenocarcinoma over the past decade--there is no place for therapeutic nihilism especially in non-ductal cancer, which represents almost 15 % of all pancreatic neoplasms.
1986年至1995年间,我们为337例胰腺导管腺癌患者、45例 Vater 壶腹癌患者和11例胰腺囊腺癌患者进行了手术。预后因素评估显示了淋巴结侵犯的影响。此外,我们还发现淋巴管和血管癌转移、肿瘤分级和肿瘤大小有显著影响。乳头癌即使在淋巴结阳性患者中也有较好的5年生存率,这是不同生物学行为的结果。我们认为,在过去十年中,导管腺癌并非没有治疗进展,尤其是在占所有胰腺肿瘤近15%的非导管癌中,不应采取治疗虚无主义。