Pickering J, Campbell H
University of Edinburgh.
Health Bull (Edinb). 2000 Sep;58(5):390-5.
To evaluate current post-splenectomy immunisation and antibiotic prophylaxis practices amongst patients splenectomised in Lothian between 1st January 1989 and 31st December 1997.
Retrospective cross-sectional study of the general practitioners of patients recorded as having had a splenectomy operation.
Lothian Health Board (population 771,000).
Asplenic patients recorded on Scottish Morbidity Records as having had a splenectomy in Lothian between 1st January 1989 and 31st December 1997.
Eighty point six percent of the patients were vaccinated against Streptococcus pneumoniae, 65.9% were vaccinated against Haemophilus influenzae, and 48.2% were vaccinated against Neisseria meningitidis; 74.8% of patients were being prescribed long-term antibiotic prophylaxis. However, only 37.4% were both vaccinated and prescribed prophylaxis as recommended, in Department of Health guidelines.
The vaccination levels seen in this survey are higher than levels reported in previously published surveys in the UK. Reported rates of post splenectomy vaccination against S. pneumoniae in both the UK and North America in 1993 ranged from 10% to 36%. However, there still remains a substantial proportion of splenectomised patients in Lothian, including some of those with the highest risk of infection, who are not vaccinated or prescribed prophylaxis as recommended.
评估1989年1月1日至1997年12月31日在洛锡安接受脾切除手术患者目前的脾切除术后免疫接种及抗生素预防措施的实施情况。
对记录有脾切除手术的患者的全科医生进行回顾性横断面研究。
洛锡安健康委员会(人口77.1万)。
1989年1月1日至1997年12月31日在洛锡安接受脾切除手术且记录在苏格兰发病率记录中的无脾患者。
80.6%的患者接种了肺炎链球菌疫苗,65.9%的患者接种了流感嗜血杆菌疫苗,48.2%的患者接种了脑膜炎奈瑟菌疫苗;74.8%的患者正在接受长期抗生素预防治疗。然而,按照卫生部指南的建议,只有37.4%的患者既接种了疫苗又接受了预防治疗。
本次调查中观察到的疫苗接种率高于英国此前发表的调查中报告的水平。1993年英国和北美的脾切除术后肺炎链球菌疫苗接种报告率在10%至36%之间。然而,在洛锡安仍有相当一部分脾切除患者,包括一些感染风险最高的患者,未按照建议接种疫苗或接受预防治疗。